Evidence map›Paper›PMID 33514883›Full record

ArticleCommunications biology2021

DeepLabStream enables closed-loop behavioral experiments using deep learning-based markerless, real-time posture detection.

Jens F Schweihoff, Matvey Loshakov, Irina Pavlova, Laura Kück, Laura A Ewell, Martin K Schwarz

Abstract readVideo-Audio Media
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Review
  10. The impact of machine learning on ethological neuroscience.Frontiers in behavioral neuroscience · 2025
    Review
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  20. Systems Neuroscience of Natural Behaviors in Rodents.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jens F SchweihoffFunctional Neuroconnectomics Group, Institute of Experimental Epileptology and Cognition Research, Medical Faculty, University of Bonn, Bonn, Germany.ORCID 0000-0002-3030-1571
Matvey LoshakovFunctional Neuroconnectomics Group, Institute of Experimental Epileptology and Cognition Research, Medical Faculty, University of Bonn, Bonn, Germany.
Irina PavlovaFunctional Neuroconnectomics Group, Institute of Experimental Epileptology and Cognition Research, Medical Faculty, University of Bonn, Bonn, Germany.
Laura KückInstitute of Experimental Epileptology and Cognition Research, Medical Faculty, University of Bonn, Bonn, Germany.
Laura A EwellInstitute of Experimental Epileptology and Cognition Research, Medical Faculty, University of Bonn, Bonn, Germany.
Martin K SchwarzFunctional Neuroconnectomics Group, Institute of Experimental Epileptology and Cognition Research, Medical Faculty, University of Bonn, Bonn, Germany. Martin.Schwarz@ukbonn.de.ORCID 0000-0002-5898-751X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In general, animal behavior can be described as the neuronal-driven sequence of reoccurring postures through time. Most of the available current technologies focus on offline pose estimation with high spatiotemporal resolution. However, to correlate behavior with neuronal activity it is often necessary to detect and react online to behavioral expressions. Here we present DeepLabStream, a versatile closed-loop tool providing real-time pose estimation to deliver posture dependent stimulations. DeepLabStream has a temporal resolution in the millisecond range, can utilize different input, as well as output devices and can be tailored to multiple experimental designs. We employ DeepLabStream to semi-autonomously run a second-order olfactory conditioning task with freely moving mice and optogenetically label neuronal ensembles active during specific head directions.

Indexed as

Behavior, AnimalDeep LearningOptogeneticsPostureVideo RecordingAnimalsConditioning, ClassicalHead MovementsImage Processing, Computer-AssistedLightMiceMice, Inbred C57BLOdorantsOlfactory PerceptionPhotic StimulationSmell

Identifiers

PMID33514883
PMCPMC7846585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.