ArticleNature communications2021
Real-time interleaved spectroscopic photoacoustic and ultrasound (PAUS) scanning with simultaneous fluence compensation and motion correction.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed.
- Differential aperture modulation enables high-fidelity 3D photoacoustic imaging.Photoacoustics · 2026Article
- Optimization of light source parameters for photoacoustic imaging: trade-offs, technologies, and clinical considerations.JPhys photonics · 2026Review
- Deep learning-driven quantitative spectroscopic photoacoustic imaging for segmentation and oxygen saturation estimation.Ultrasonics · 2026Article
- Fabrication of optically transparent ultrasound transducers to integrate light and sound in multimodal biomedical systems.Nature protocols · 2026Review
- Complementary fluorescence and photoacoustic imaging of tozuleristide in muscle tissue in vitro- toward optically-guided solid tumor surgery: feasibility studies.Scientific reports · 2026Article
- Mapping glucose-induced hemodynamics in white fat depots with label-free optoacoustics.Photoacoustics · 2026Article
- Rotational ultrasound and photoacoustic tomography of the human body.Nature biomedical engineering · 2026Article
- Motion score for spectral quality control of optoacoustic-ultrasound data.Scientific reports · 2026Article
- Unified linear-concave transducer enabling 100 Hz plane-wave ultrasound and photoacoustic dynamic imaging.Biomedical optics express · 2025Article
- A three-dimensional photoacoustic and ultrasound automated breast volume scanner (PAUS-ABVS) for breast cancer patients.Science advances · 2025Article
- Clinical ultrasound, photoacoustic, and fluorescence image-guided lymphovenous anastomosis microsurgery via a transparent ultrasound transducer array.Nature communications · 2025Article
- Transformer-based optical attenuation compensation and denoising in photoacoustic imaging.Journal of biomedical optics · 2025Article
- Research advances in intramuscular fat deposition and chicken meat quality: genetics and nutrition.Journal of animal science and biotechnology · 2025Review
- Label-Free Dual-Modal Photoacoustic/Ultrasound Localization Imaging for Studying Acute Kidney Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Clinical application of photoacoustic imaging for cervical precursor lesion detection.Journal of medical ultrasonics (2001) · 2025Article
- Joint segmentation and image reconstruction with error prediction in photoacoustic imaging using deep learning.Photoacoustics · 2024Article
- Spiral volumetric optoacoustic and ultrasound (SVOPUS) tomography of mice.Photoacoustics · 2024Article
- TowardsFundamental research · 2024Review
- Challenges and advances in two-dimensional photoacoustic computed tomography: a review.Journal of biomedical optics · 2024Review
- Multimodal optoacoustic imaging: methods and contrast materials.Chemical Society reviews · 2024Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For over two decades photoacoustic imaging has been tested clinically, but successful human trials have been limited. To enable quantitative clinical spectroscopy, the fundamental issues of wavelength-dependent fluence variations and inter-wavelength motion must be overcome. Here we propose a real-time, spectroscopic photoacoustic/ultrasound (PAUS) imaging approach using a compact, 1-kHz rate wavelength-tunable laser. Instead of illuminating tissue over a large area, the fiber-optic delivery system surrounding an US array sequentially scans a narrow laser beam, with partial PA image reconstruction for each laser pulse. The final image is then formed by coherently summing partial images. This scheme enables (i) automatic compensation for wavelength-dependent fluence variations in spectroscopic PA imaging and (ii) motion correction of spectroscopic PA frames using US speckle tracking in real-time systems. The 50-Hz video rate PAUS system is demonstrated in vivo using a murine model of labelled drug delivery.
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