Evidence map›Paper›PMID 33514616›Full record

ArticleBMJ case reports2021

Misoprostol-augmented induction of labour for third trimester fetal demise in a patient with prior hysterotomies.

Isabel Beshar, Karolina Thomson, James Byrne

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Isabel BesharStanford University School of Medicine, Stanford, California, USA ibeshar@stanford.edu.ORCID http://orcid.org/0000-0002-4367-836X
Karolina ThomsonObstetrics & Gynecology, Santa Clara Valley Medical Center, San Jose, California, USA.
James ByrneMaternal Fetal Medicine, Obstetrics and Gynecology, Santa Clara Valley Medical Center, San Jose, California, USA.
Santa Clara Valley Medical Center · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 31-year-old G3P2002 with history of two prior caesarean sections presented with influenza-like illness, requiring intubation secondary to acute respiratory distress syndrome. Investigations revealed intrauterine fetal demise at 30-week gestation.She soon deteriorated with sepsis and multiple organs impacted. Risks of the gravid uterus impairing cardiopulmonary function appeared greater than risks of delivery, including that of uterine rupture. Vaginal birth after caesarean was achieved with misoprostol and critical care status rapidly improved.Current guidelines for management of fetal demise in patients with prior hysterotomies are mixed: although the American College of Obstetricians and Gynecologists recommends standard obstetric protocols rather than misoprostol administration for labour augmentation, there is limited published data citing severe maternal morbidity associated with misoprostol use. This case report argues misoprostol-augmented induction of labour can be a reasonable option in a medically complex patient with fetal demise and prior hysterotomies.

Indexed as

Administration, IntravaginalAdultDelivery, ObstetricFemaleFetal DeathHumansHysterotomyIntubation, IntratrachealLabor, InducedLabor, ObstetricMisoprostolMultiple Organ FailureOxytocicsPregnancyPregnancy Complications, InfectiousPregnancy Trimester, ThirdMisoprostolOxytocicsadult intensive caregynaecology and fertilityobstetricspregnancyreproductive medicinerespiratory system

Identifiers

PMID33514616
PMCPMC7849869
OpenAlexW3121832466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.