Evidence map›Paper›PMID 33514603›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2021

Race and Patient-reported Symptoms in Adherence to Adjuvant Endocrine Therapy: A Report from the Women's Hormonal Initiation and Persistence Study.

Vanessa B Sheppard, Arnethea L Sutton, Alejandra Hurtado-de-Mendoza, Jun He, Bassam Dahman, Megan C Edmonds, Mary Helen Hackney, Mahlet G Tadesse

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Observational
  6. Interventions to improve adherence to oral endocrine therapy for prevention or treatment of breast cancer in Black women of low socioeconomic status.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  9. A Cohort Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms: Results from ECOG-ACRIN E1Z11.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Vanessa B SheppardDepartment of Health Behavior and Policy, Virginia Commonwealth University School of Medicine, Richmond, Virginia. vanessa.sheppard@vcuhealth.org.
Arnethea L SuttonDepartment of Health Behavior and Policy, Virginia Commonwealth University School of Medicine, Richmond, Virginia.ORCID 0000-0002-4398-0278
Alejandra Hurtado-de-MendozaDepartment of Oncology, Georgetown University Medical Center, Washington, DC.
Jun HeDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
Bassam DahmanDepartment of Health Behavior and Policy, Virginia Commonwealth University School of Medicine, Richmond, Virginia.
Megan C EdmondsDepartment of Health Behavior and Policy, Virginia Commonwealth University School of Medicine, Richmond, Virginia.
Mary Helen HackneyDepartment of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, Virginia.ORCID 0000-0002-3460-9573
Mahlet G TadesseDepartment of Mathematics and Statistics, Georgetown University, Washington, DC.
Virginia Commonwealth University · USGeorgetown University · USMayo Clinic in Florida · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Kim Felder Rhoads · 1985 to 2026
$51.0M
Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
Institutional Career Development CoreKL2TR001432 · NCATS · GEORGETOWN UNIVERSITY · PI UMANS, JASON G · 2015 to 2024
$7.5M
Training Program in Cancer Prevention and Control and Cancer Health Equity (CPC-CHE)T32CA093423 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Bernard F Fuemmeler, Oxana G Palesh · 2018 to 2026
$3.0M
PREDICTORS OF ADJUVANT ENDOCRINE THERAPY ADHERENCE IN WOMEN WITH BREAST CANCERR01CA154848 · NCI · GEORGETOWN UNIVERSITY · PI SHEPPARD, VANESSA B · 2011 to 2015
$2.5M
NCATS NIH HHS KL2 TR001432NCATS NIH HHS UL1 TR002649NCI NIH HHS P30 CA016059NCI NIH HHS R01 CA154848NCI NIH HHS T32 CA093423
6 · The paper itself

Abstract

backgroundAdjuvant endocrine therapy (AET) improves outcomes in women with hormone receptor-positive (HR

methodsThe Women's Hormonal Initiation and Persistence study included women diagnosed with nonrecurrent HR

resultsOf the 570 participants, 92% were privately insured and nearly one of three were Black. Thirty-six percent reported nonadherent behaviors. In multivariable analysis, women less likely to report adherent behaviors were Black (vs. White; OR, 0.43; 95% CI, 0.27-0.67;

conclusionsRacial differences in AET adherence were observed. Longitudinal assessments of symptom burden are needed to better understand this dynamic process and factors that may explain differences in survivor subgroups. IMPACT: Future interventions should prioritize Black survivors and women with greater symptom burden.

Indexed as

Ethnic and Racial MinoritiesMedication AdherenceAdultAgedAged, 80 and overAntineoplastic Agents, HormonalAromatase InhibitorsBreast NeoplasmsFemaleHumansMiddle AgedReceptors, EstrogenTamoxifenUnited StatesAntineoplastic Agents, HormonalAromatase InhibitorsReceptors, EstrogenTamoxifen

Identifiers

PMID33514603
PMCPMC8330157
OpenAlexW3122116691

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.