ArticleScience advances2021
An electronic proton-trapping ion pump for selective drug delivery.
Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 39 citations in OpenAlex.
- Iontronic click-to-release enables electrically controlled delivery of drugs and biomolecules beyond charge and size limitations.Nature communications · 2026Article
- Controlling Cell Migratory Patterns Under an Electric Field Regulated by a Neural Network-Based Feedback Controller.Bioengineering (Basel, Switzerland) · 2025Article
- Implantable bioelectronic devices for photoelectrochemical and electrochemical modulation of cells and tissues.Nature reviews bioengineering · 2025Article
- Organic Bioelectronics in Microphysiological Systems: Bridging the Gap Between Biological Systems and Electronic Technologies.Biosensors · 2025Review
- Roadmap on multifunctional materials for drug delivery.JPhys materials · 2024Review
- Delivering biochemicals with precision using bioelectronic devices enhanced with feedback control.PloS one · 2024Article
- Organic Electronics in Biosensing: A Promising Frontier for Medical and Environmental Applications.Biosensors · 2023Review
- Chemically revised conducting polymers with inflammation resistance for intimate bioelectronic electrocoupling.Bioactive materials · 2023Review
- The Influence of Regiochemistry on the Performance of Organic Mixed Ionic and Electronic Conductors.Angewandte Chemie (International ed. in English) · 2023Article
- The Influence of Regiochemistry on the Performance of Organic Mixed Ionic and Electronic Conductors.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2023Article
- Streamlining the interface between electronics and neural systems for bidirectional electrochemical communication.Chemical science · 2023Review
- Advanced Temporally-Spatially Precise Technologies for On-Demand Neurological Disorder Intervention.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The organic electronic ion pump (OEIP) delivers ions and charged drugs from a source electrolyte, through a charge-selective membrane, to a target electrolyte upon an electric bias. OEIPs have successfully delivered γ-aminobutyric acid (GABA), a neurotransmitter that reduces neuronal excitations, in vitro, and in brain tissue to terminate induced epileptic seizures. However, during pumping, protons (H
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.