Evidence map›Paper›PMID 33514383›Full record

ReviewBMC veterinary research2021

Emerging interactions between diet, gastrointestinal helminth infection, and the gut microbiota in livestock.

Andrew R Williams, Laura J Myhill, Sophie Stolzenbach, Peter Nejsum, Helena Mejer, Dennis S Nielsen, Stig M Thamsborg

Open access · goldAbstract readReview
In one paragraph

Review in BMC veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Gut Microbiota of Ruminants and Monogastric Livestock: An Overview.Animals : an open access journal from MDPI · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Serological Assessment ofPathogens (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrew R WilliamsDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark. arw@sund.ku.dk.ORCID http://orcid.org/0000-0002-8231-282X
Laura J MyhillDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Sophie StolzenbachDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Peter NejsumDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Helena MejerDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
Dennis S NielsenDepartment of Food Science, University of Copenhagen, Copenhagen, Denmark.
Stig M ThamsborgDepartment of Veterinary and Animal Sciences, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DK

Funding

Danmarks Frie Forskningsfond 4184-00377Danmarks Frie Forskningsfond 7026-00094B
6 · The paper itself

Abstract

Increasing evidence suggests that nutritional manipulation of the commensal gut microbiota (GM) may play a key role in maintaining animal health and production in an era of reduced antimicrobial usage. Gastrointestinal helminth infections impose a considerable burden on animal performance, and recent studies suggest that infection may substantially alter the composition and function of the GM. Here, we discuss the potential interactions between different bioactive dietary components (prebiotics, probiotics and phytonutrients) and helminth infection on the GM in livestock. A number of recent studies suggest that host diet can strongly influence the nature of the helminth-GM interaction. Nutritional manipulation of the GM may thus impact helminth infection, and conversely infection may also influence how the GM responds to dietary interventions. Moreover, a dynamic interaction exists between helminths, the GM, intestinal immune responses, and inflammation. Deciphering the mechanisms underlying the diet-GM-helminth axis will likely inform future helminth control strategies, as well as having implications for how health-promoting feed additives, such as probiotics, can play a role in sustainable animal production.

Indexed as

DietAnimalsGastrointestinal DiseasesGastrointestinal MicrobiomeHelminthiasis, AnimalHelminthsIntestinal Diseases, ParasiticLivestockPrebioticsProbioticsPrebioticsDietGut microbiotaHelminthsimmunityLivestockprebioticsprobiotics

Identifiers

PMID33514383
PMCPMC7845040
OpenAlexW3123528750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.