Evidence map›Paper›PMID 33513898›Full record

ArticleJournal of cardiovascular development and disease2021

A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation.

Nimrat Grewal, Bart J J Velders, Adriana C Gittenberger-de Groot, Robert Poelmann, Robert J M Klautz, Thomas J Van Brakel, Jan H N Lindeman

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. The role of transforming growth factor beta in bicuspid aortic valve aortopathy.Indian journal of thoracic and cardiovascular surgery · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nimrat GrewalDepartment of Cardiothoracic Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Bart J J VeldersDepartment of Cardiothoracic Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0002-3999-4220
Adriana C Gittenberger-de GrootDepartment of Anatomy and Embryology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Robert PoelmannInstitute of Biology, Animal Sciences and Health, Leiden University, 2333 BE Leiden, The Netherlands.
Robert J M KlautzDepartment of Cardiothoracic Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Thomas J Van BrakelDepartment of Cardiothoracic Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.ORCID 0000-0001-6933-1797
Jan H N LindemanDepartment of Vascular Surgery, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Leiden University Medical Center · NLLeiden University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The pathophysiologic basis of an acute type A aortic dissection (TAAD) is largely unknown. In an effort to evaluate vessel wall defects, we systematically studied aortic specimens in TAAD patients. (2) Methods: Ascending aortic wall specimens (

Indexed as

acute aortic syndromeaortacardiovascular disease

Identifiers

PMID33513898
PMCPMC7911401
OpenAlexW3125215601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.