Evidence map›Paper›PMID 33513877›Full record

ArticleCancers2021

Preoperative CTC-Detection by CellSearch

Harald Hugenschmidt, Knut Jørgen Labori, Elin Borgen, Cathrine Brunborg, Cecilie Bendigtsen Schirmer, Lars Thomas Seeberg, Bjørn Naume, Gro Wiedswang

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Harald HugenschmidtInstitute of Clinical Medicine, University of Oslo, 0424 Oslo, Norway.ORCID 0000-0002-1114-5366
Knut Jørgen LaboriInstitute of Clinical Medicine, University of Oslo, 0424 Oslo, Norway.
Elin BorgenDepartment of Pathology, Oslo University Hospital, 0424 Oslo, Norway.
Cathrine BrunborgOslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, 0424 Oslo, Norway.
Cecilie Bendigtsen SchirmerDepartment of Pathology, Oslo University Hospital, 0424 Oslo, Norway.
Lars Thomas SeebergDepartment of Gastrointestinal Surgery, Oslo University Hospital, 0424 Oslo, Norway.
Bjørn NaumeInstitute of Clinical Medicine, University of Oslo, 0424 Oslo, Norway.
Gro WiedswangDepartment of Gastrointestinal Surgery, Oslo University Hospital, 0424 Oslo, Norway.
Oslo University Hospital · NO

Funding

Helse Sør-Øst RHF Research grant, covering the costs of laboratory analyses and a part-time junior researcher position for H.H. in the beginning of the study
6 · The paper itself

Abstract

In patients with presumed pancreatic ductal adenocarcinoma (PDAC), biomarkers that may open for personalised, risk-adapted treatment are lacking. The study analysed the impact of CTCs-presence on the patterns of recurrence and survival in 98 patients resected for PDAC with 5-10 years of follow-up. Preoperative samples were analysed by the CellSearch

Indexed as

CellSearch®circulating tumour cellsCTCmetastasispancreatic cancerprognosticationrecurrencesurgical resection

Identifiers

PMID33513877
PMCPMC7865868
OpenAlexW3122999439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.