Evidence map›Paper›PMID 33513874›Full record

ArticleNutrients2021

Chronic Oleoylethanolamide Treatment Decreases Hepatic Triacylglycerol Level in Rat Liver by a PPARγ/SREBP-Mediated Suppression of Fatty Acid and Triacylglycerol Synthesis.

Adele Romano, Marzia Friuli, Laura Del Coco, Serena Longo, Daniele Vergara, Piero Del Boccio, Silvia Valentinuzzi, Ilaria Cicalini, Francesco P Fanizzi, Silvana Gaetani and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

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  8. Bee Venom and Its Major Component Melittin AttenuatedInternational journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Adele RomanoDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.
Marzia FriuliDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.
Laura Del CocoDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Via Prov.le Lecce-Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-4805-7538
Serena LongoDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Via Prov.le Lecce-Monteroni, 73100 Lecce, Italy.ORCID 0000-0001-8595-1259
Daniele VergaraDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Via Prov.le Lecce-Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-2396-7674
Piero Del BoccioDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0003-1653-2194
Silvia ValentinuzziDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Ilaria CicaliniCenter for Advanced Studies and Technology (CAST), University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-9792-2225
Francesco P FanizziDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Via Prov.le Lecce-Monteroni, 73100 Lecce, Italy.ORCID 0000-0003-3073-5772
Silvana GaetaniDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy.
Anna M GiudettiDepartment of Biological and Environmental Sciences and Technologies, University of Salento, Via Prov.le Lecce-Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-9204-040X
University of Salento · ITSapienza University of Rome · ITUniversity of Chieti-Pescara · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2017XZMBYX_004 to SG
6 · The paper itself

Abstract

Oleoylethanolamide (OEA) is a naturally occurring bioactive lipid belonging to the family of N-acylethanolamides. A variety of beneficial effects have been attributed to OEA, although the greater interest is due to its potential role in the treatment of obesity, fatty liver, and eating-related disorders. To better clarify the mechanism of the antiadipogenic effect of OEA in the liver, using a lipidomic study performed by

Indexed as

AnimalsCell Line, TumorChromatography, LiquidDiacylglycerol O-AcyltransferaseEndocannabinoidsFatty AcidsLipogenesisLiverMagnetic Resonance SpectroscopyMaleMultivariate AnalysisOleic AcidsPPAR gammaRatsRats, WistarStearoyl-CoA DesaturaseDiacylglycerol O-AcyltransferaseEndocannabinoidsFatty AcidsOleic AcidsoleoylethanolamidePPAR gammaSrebf1 protein, ratStearoyl-CoA DesaturaseSterol Regulatory Element Binding Protein 1Triglycerideslipid metabolismNMR spectroscopyoleoylethanolamideperoxisome proliferator-activated receptorγsphingolipids

Identifiers

PMID33513874
PMCPMC7910994
OpenAlexW3122300243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.