Evidence map›Paper›PMID 33513754›Full record

ReviewInternational journal of molecular sciences2021

Molecular Iodine Has Extrathyroidal Effects as an Antioxidant, Differentiator, and Immunomodulator.

Carmen Aceves, Irasema Mendieta, Brenda Anguiano, Evangelina Delgado-González

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
  2. Molecular Iodine/Cells · 2026
    Article
  3. Evolving Concepts in Gestational Iodine Requirements.Healthcare (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Evolution of the iodine cycle and the late stabilization of the Earth's ozone layer.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. The roles of essential trace elements in T cell biology.Journal of cellular and molecular medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carmen AcevesInstituto de Neurobiología, UNAM-Juriquilla, Boulevard Juriquilla 3001, Juriquilla, Querétaro 76230, Mexico.ORCID 0000-0001-9418-8304
Irasema MendietaInstituto de Neurobiología, UNAM-Juriquilla, Boulevard Juriquilla 3001, Juriquilla, Querétaro 76230, Mexico.
Brenda AnguianoInstituto de Neurobiología, UNAM-Juriquilla, Boulevard Juriquilla 3001, Juriquilla, Querétaro 76230, Mexico.ORCID 0000-0002-7744-8685
Evangelina Delgado-GonzálezInstituto de Neurobiología, UNAM-Juriquilla, Boulevard Juriquilla 3001, Juriquilla, Querétaro 76230, Mexico.

Funding

Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México 203919Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México 209717Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México Posdoc grant Irasema Mendieta
6 · The paper itself

Abstract

Most investigations of iodine metabolism in humans and animals have focused on its role in thyroid function. However, considerable evidence indicates that iodine could also be implicated in the physiopathology of other organs. We review the literature that shows that molecular iodine (I

Indexed as

AnimalsAntineoplastic AgentsAntioxidantsApoptosisCell DifferentiationCell ProliferationGene Expression Regulation, NeoplasticHumansImmunologic FactorsIodineMitochondriaNeoplasmsPPAR gammaAntineoplastic AgentsAntioxidantsImmunologic FactorsIodinePPAR gammaantioxidantcancerdifferentiatorimmune modulatormitochondriamolecular iodineperoxisome proliferator-activated receptor (ppar)

Identifiers

PMID33513754
PMCPMC7865438
OpenAlexW3123998197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.