ArticleCurrent biology : CB2021
The Genetic Architecture of Variation in the Sexually Selected Sword Ornament and Its Evolution in Hybrid Populations.
Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 39 citations in OpenAlex.
- Inversion characterization inbioRxiv : the preprint server for biology · 2026Article
- Divergent habitat selection across many loci maintains species boundaries during introgression.bioRxiv : the preprint server for biology · 2026Article
- Sensitivity of genome-wide tests for mitonuclear genetic incompatibilities.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Article
- Cis-regulatory evolution of Wnt family genes contributes to a morphological difference between silkworm species.PLoS biology · 2026Article
- Genomic signatures of reproductive isolation are decoupled from floral divergence in a long-standing hybrid zone.bioRxiv : the preprint server for biology · 2026Article
- Admixture Mapping Reveals Evidence for Multiple Mitonuclear Incompatibilities in Swordtail Fish Hybrids.Molecular ecology · 2025Article
- Cis-regulatory evolution ofbioRxiv : the preprint server for biology · 2025Article
- Pervasive gene flow despite strong and varied reproductive barriers in swordtails.Nature ecology & evolution · 2025Article
- Functional test of a naturally occurred tumor modifier gene provides insights to melanoma development.G3 (Bethesda, Md.) · 2025Article
- Recurrent evolution of small body size and loss of the sword ornament in Northern swordtail fish.Evolution; international journal of organic evolution · 2024Article
- The Ecology of Hybrid Incompatibilities.Cold Spring Harbor perspectives in biology · 2024Review
- Phylogenomic analyses of all species of swordtail fishes (genus Xiphophorus) show that hybridization preceded speciation.Nature communications · 2024Article
- Swordtail fish hybrids reveal that genome evolution is surprisingly predictable after initial hybridization.PLoS biology · 2024Article
- Pervasive gene flow despite strong and varied reproductive barriers in swordtails.bioRxiv : the preprint server for biology · 2024Article
- The temporal and genomic scale of selection following hybridization.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The Genetic Basis Underpinning Sexually Selected Traits across Different Animal Lineages: Are There Genetic Mechanisms in Common?Animals : an open access journal from MDPI · 2024Review
- Article
- Validity of Xiphophorus fish as models for human disease.Disease models & mechanisms · 2024Review
- Genome evolution is surprisingly predictable after initial hybridization.bioRxiv : the preprint server for biology · 2023Article
- Sex-biased gene expression at single-cell resolution: cause and consequence of sexual dimorphism.Evolution letters · 2023Article
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9 authors at 6 institutions in 4 countries.
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Abstract
Biologists since Darwin have been fascinated by the evolution of sexually selected ornaments, particularly those that reduce viability. Uncovering the genetic architecture of these traits is key to understanding how they evolve and are maintained. Here, we investigate the genetic architecture and evolutionary loss of a sexually selected ornament, the "sword" fin extension that characterizes many species of swordtail fish (Xiphophorus). Using sworded and swordless sister species of Xiphophorus, we generated a mapping population and show that the sword ornament is polygenic-with ancestry across the genome explaining substantial variation in the trait. After accounting for the impacts of genome-wide ancestry, we identify one major-effect quantitative trait locus (QTL) that explains ~5% of the overall variation in the trait. Using a series of approaches, we narrow this large QTL interval to several likely candidate genes, including genes involved in fin regeneration and growth. Furthermore, we find evidence of selection on ancestry at one of these candidates in four natural hybrid populations, consistent with selection against the sword in these populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.