Evidence map›Paper›PMID 33512784›Full record

ReviewACR open rheumatology2021

Takayasu Arteritis: a Systematic Review and Meta-Analysis of Test Accuracy and Benefits and Harms of Common Treatments.

Anisha B Dua, Mohamad A Kalot, Nedaa M Husainat, Kevin Byram, Jason M Springer, Karen E James, Yih Chang Lin, Marat Turgunbaev, Alexandra Villa-Forte, Andy Abril and 4 more

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in ACR open rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06807788 (Evaluation of Platelet Aggregability in Patients with Takayasu's Arteritis), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06807788 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of Platelet Aggregability in Patients with Takayasu's Arteritis

TypeobservationalSponsorJose Carlos NicolauRan2024 to 2027Enrolled100ConditionsTakayasu Arteritis (TAK), Vasculitis, SystemicArmsClopidogrel
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  8. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  9. A 29-year-old woman with recurrent syncope.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 1 country.

Anisha B DuaNorthwestern University Feinberg School of Medicine, Chicago, Illinois.
Mohamad A KalotState University of New York at Buffalo.ORCID https://orcid.org/0000-0002-6581-4561
Nedaa M HusainatSt. Mary's Hospital, Saint Louis, Missouri.ORCID https://orcid.org/0000-0002-9638-2992
Kevin ByramVanderbilt University Medical Center, Nashville, Tennessee.
Jason M SpringerVanderbilt University Medical Center, Nashville, Tennessee.ORCID https://orcid.org/0000-0002-3903-6049
Karen E JamesUniversity of Utah Health, Salt Lake City.
Yih Chang LinUniversity of South Florida, Tampa.
Marat TurgunbaevAmerican College of Rheumatology, Atlanta, Georgia.
Alexandra Villa-ForteCleveland Clinic, Cleveland, Ohio.
Andy AbrilMayo Clinic, Jacksonville, Florida.
Carol LangfordCleveland Clinic, Cleveland, Ohio.
Mehrdad MazUniversity of Kansas Medical Center, Kansas City.
Sharon A ChungUniversity of California, San Francisco Medical Center.
Reem A MustafaUniversity of Kansas Medical Center, Kansas City.
Cleveland Clinic · USUniversity of Kansas Medical Center · USVanderbilt University Medical Center · USAmerican College of Rheumatology · USJacksonville College · USNorthwestern University · USSt. Mary's Hospital · USUniversity at Buffalo, State University of New York · USUniversity of California San Francisco Medical Center · USUniversity of South Florida · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTakayasu's arteritis (TAK) is a granulomatous large-vessel vasculitis primarily affecting the aorta and its proximal branches. TAK can be a difficult disease to diagnose and manage given the rarity of the disease as well as current limitations in biomarkers, imperfect imaging modalities, and few randomized controlled trials.

methodsIn developing the American College of Rheumatology/Vasculitis Foundation guideline for the management of TAK, we performed an extensive systematic literature review to guide our recommendations. We included RCTs first. When RCTs were not available, we included observational studies that reported on patient-important outcomes for the intervention and comparison. When studies with comparative data were not available, we included case series that present patient-important outcomes for either the intervention or the comparison.

resultsThree hundred forty-seven articles were included for full review to answer 27 population, intervention, comparison, and outcome questions related to TAK. Ten studies were evaluated that addressed the use of glucocorticoids (GCs), non-GC nonbiologic therapies, as well as biologics in treating TAK. A total of 33 studies, including 8 comparative studies, were included to determine the test accuracy of commonly available diagnostic tests for TAK.

conclusionThis comprehensive systematic review synthesizes and evaluates the benefits and harms of different treatment options and the accuracy of commonly used tests for the management of TAK.

Identifiers

PMID33512784
PMCPMC7882531
OpenAlexW4205634383

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.