ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2021
Dutch utility weights for the EORTC cancer-specific utility instrument: the Dutch EORTC QLU-C10D.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Evolving Landscape of Discrete Choice Experiments in Health Economics: A Systematic Review.PharmacoEconomics · 2025Pooled it
- Discrete Choice Experiments in Health State Valuation: A Systematic Review of Progress and New Trends.Applied health economics and health policy · 2023Pooled it
- Assessing the health utility values of patients with six common cancers in China using the QLU-C10D: A cross-sectional survey.iScience · 2026Article
- Cancer specific health utilities - QLU-C10D country value sets for Belgium, Hungary, Portugal and the Republic of Korea - an international valuation study.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- United Kingdom value set for the functional assessment of cancer therapy eight dimension (FACT-8D) preference-based quality of life instrument.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Comparing EQ-5D-5L and SF-6Dv2 utilities with QLU-C10D utilities in hematologic cancer patients.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Developing a patient-based utility value set for the EORTC QLU-C10D using the OPUF method in Chinese cancer patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Japanese value set for the Functional Assessment of Cancer Therapy Eight Dimension (FACT-8D) cancer-specific preference-based quality of life instrument.Health and quality of life outcomes · 2025Article
- Validation of the Cancer-Specific Preference-Based Measure EORTC QLU-C10D against the Generic Instruments EQ-5D-5L and SF-6Dv2 in a Prospectively Collected Sample of Patients with Cancer in Austria and France.PharmacoEconomics · 2025Article
- Cost and Cost-Effectiveness of Treating Human Epidermal Growth Factor Receptor 2-Low Metastatic Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025Article
- Validation of the cancer-specific utility measure EORTC QLU-C10D using evidence from four lung cancer trials covering six country value sets.Scientific reports · 2025Article
- Norwegian and Swedish value sets for the EORTC QLU-C10D utility instrument.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Developing a utility value set for the Gambling Quality of Life Scale-Brief (GQoLS-Brief) using a discrete choice experiment.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Valuation of the EORTC Quality of Life Utility Core 10 Dimensions (QLU-C10D) in a Multi-ethnic Asian Setting: How Does Having Cancer Matter?PharmacoEconomics · 2024Article
- Chinese utility weights for the EORTC cancer-specific utility instrument QLU-C10D.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- The EORTC QLU-C10D is a valid cancer-specific preference-based measure for cost-utility and health technology assessment in the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- A comparison of measurement properties between EORTC QLU-C10D and FACT-8D in patients with hematological malignances.Health economics review · 2024Article
- Cost-effectiveness of proton beam therapy vs. conventional radiotherapy for patients with brain tumors in Sweden: results from a non-randomized prospective multicenter study.Cost effectiveness and resource allocation : C/E · 2024Article
- Japanese value set for the EORTC QLU-C10D: A multi-attribute utility instrument based on the EORTC QLQ-C30 cancer-specific quality-of-life questionnaire.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Cancer-Specific Health Utilities: Evaluation of Core Measurement Properties of the EORTC QLU-C10D in Lung Cancer Patients-Data from Four Multicentre LUX-Lung Trials, Applying Six Country Tariffs.PharmacoEconomics - open · 2024Article
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8 authors.
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Abstract
purposeTo measure utilities among cancer patients, a cancer-specific utility instrument called the European Organization for Research and Treatment of Cancer (EORTC) QLU-C10D has been developed based on EORTC quality of life core module (QLQ-C30). This study aimed to provide Dutch utility weights for the QLU-C10D.
methodsA cross-sectional valuation study was performed in 1017 participants representative in age and gender of the Dutch general population. The valuation method was a discrete choice experiment containing 960 choice sets, i.e. pairs of QLU-C10D health states, each health state described in terms of the 10 QLU-C10D domains and the duration of that health state. Each participant considered 16 choice sets, choosing their preferred health state from each pair. Utility scores were derived using generalized estimation equation models. Non-monotonic levels were combined.
resultsUtility decrements were generated for all 10 QLU-C10D domains, with largest decrements for pain (- 0.242), physical functioning (- 0.228), and role functioning (- 0.149). Non-monotonic levels of emotional functioning, pain, fatigue, sleep problems, and appetite loss were combined. No decrement in utility was seen in case of a little or quite a bit impairment in emotional functioning or a little pain. The mean QLU-C10D utility score of the participants was 0.85 (median = 0.91, interquartile range = 0.82 to 0.96).
conclusionDutch utility decrements were generated for the QLU-C10D. These are important for evaluating the cost-utility of new cancer treatments and supportive care interventions. Further insight is warranted into the added value of the QLU-C10D alongside other utility instruments.
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