Evidence map›Paper›PMID 33512643›Full record

ArticleCell and tissue research2021

CCN2/CTGF promotor activity in the developing and adult mouse eye.

Andrea E Dillinger, Sabrina Kuespert, Franziska Froemel, Ernst R Tamm, Rudolf Fuchshofer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell and tissue research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. CCN2/CTGF-A Modulator of the Optic Nerve Head Astrocyte.Frontiers in cell and developmental biology · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andrea E DillingerInstitute of Human Anatomy and Embryology, University of Regensburg, 93053, Regensburg, Germany.
Sabrina KuespertInstitute of Human Anatomy and Embryology, University of Regensburg, 93053, Regensburg, Germany.
Franziska FroemelInstitute of Human Anatomy and Embryology, University of Regensburg, 93053, Regensburg, Germany.
Ernst R TammInstitute of Human Anatomy and Embryology, University of Regensburg, 93053, Regensburg, Germany.
Rudolf FuchshoferInstitute of Human Anatomy and Embryology, University of Regensburg, 93053, Regensburg, Germany. rudolf.fuchshofer@ur.de.ORCID http://orcid.org/0000-0002-0474-6980

Funding

Deutsche Forschungsgemeinschaft DFG FU734/6-1
6 · The paper itself

Abstract

CCN2/CTGF is a matricellular protein that is known to enhance transforming growth factor-β signaling and to induce a myofibroblast-like phenotype in a variety of cell types. Here, we investigated Ccn2/Ctgf promotor activity during development and in the adult mouse eye, using CTGF

Indexed as

Endothelial CellsRetinaAnimalsConnective Tissue Growth FactorMicePromoter Regions, GeneticCCN2 protein, mouseConnective Tissue Growth FactorAstrocyteEye developmentGlial laminaNeural crestTrabecular meshwork

Identifiers

PMID33512643
PMCPMC8211604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.