ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2021
Inverted internal limiting membrane flap technique in eyes with large idiopathic full-thickness macular hole: long-term functional and morphological outcomes.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- 360° inverted internal limiting membrane flap technique for idiopathic macular holes ≤ 250 µm, > 250 and ≤ 400 µm, and > 400 µm.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Trial
- EFFICACY AND SAFETY OF AMNIOTIC MEMBRANE TRANSPLANTATION IN VITRECTOMY FOR EXTRA-LARGE OR LONG-STANDING MACULAR HOLES: A Prospective Clinical Study.Retina (Philadelphia, Pa.) · 2026Observational
- Application of subretinal injection of balanced salt solution for the management of large-diameter macular holes.BMC ophthalmology · 2026Article
- Prediction of visual recovery after idiopathic macular hole surgery: a triad of tractional mechanics, subfoveal anatomy, and preoperative function.International journal of ophthalmology · 2026Article
- Macular hole surgery in times of the COVID-19 pandemic.Scientific reports · 2025Article
- Changes in vascular density in the macula after pars plana vitrectomy for idiopathic macular hole with macular peeling and one type of flap.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2024Article
- Effect of internal limiting membrane surgical techniques on the idiopathic and refractory management of macular holes: a systematic review and meta-analysis.International journal of retina and vitreous · 2024Review
- Retinal displacement after surgery for idiopathic macular hole.International journal of ophthalmology · 2024Review
- Microperimetric evaluation and predictive factors of visual recovery after successful inverted internal limiting membrane-flap technique for macular hole in high myopic eyes.Frontiers in medicine · 2023Article
- Visual improvement and regeneration of retinal layers in eyes with small, medium, and large idiopathic full-thickness macular holes treated with the inverted internal limiting membrane flap technique over a period of 12 months.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- [iOCT in clinical use : Correlation of intraoperative morphology and postoperative visual outcome in patients with full thickness macular hole].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2022Observational
- Inverted Internal Limiting Membrane Flap Technique: Is It the Best Option for Macular Holes?Clinical ophthalmology (Auckland, N.Z.) · 2021Review
- Intraoperative Observation of a Macular Holes Using Optical Coherence Tomography.Clinical optometry · 2021Article
- Postoperative retinal microstructure and functional outcome after inverted-flap technique associated with silicone oil tamponade in macular hole surgery.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
- Long-Shaft Vitrectomy Probe for Vitreoretinal Diseases in Highly Myopic Eyes: A Randomized Controlled Trial.Ophthalmology scienceArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
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Abstract
purposeTo investigate morphological and functional outcomes of the inverted internal limiting membrane (I-ILM) flap technique in large (≥ 400 μm) idiopathic full-thickness macular holes (FTMH) over a follow-up period of 12 months.
methodsIn this retrospective study, 55 eyes of 54 consecutive patients were enrolled. Best-corrected visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT, Heidelberg, Spectralis) were performed preoperatively as well as 1, 3, 6, 9, and 12 months postoperatively. Special focus was put on the reintegration of outer retinal layers and the different ILM flap appearances.
resultsFTMH closure rate was 100% (55/55). BCVA significantly improved over the follow-up period of 12 months from 0.98 ± 0.38 LogMAR preoperatively to 0.42 ± 0.33 LogMAR at 12 months postoperatively (p < 0.001). There was no significant correlation between the three different ILM flap appearances and BCVA. Better preoperative BCVA, complete restoration of the external limiting membrane (ELM), higher macular hole index (MHI), and smaller MH base diameter were associated with higher improvement of BCVA.
conclusionOur study highlights the favorable morphological and functional outcomes of the I-ILM flap technique in the short as well as in the long term. While complete ELM restoration revealed to be an important factor for improvement in BCVA, the different postoperative ILM flap appearances seem not to be related to BCVA.
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