Evidence map›Paper›PMID 33512511›Full record

ArticleJournal of public health (Oxford, England)2022

Determinants of stage at diagnosis of HPV-related cancer including area deprivation and clinical factors.

Rohini Chakravarthy, Sarah C Stallings, Digna R Velez Edwards, Sifang Kathy Zhao, Douglas Conway, J Sunil Rao, Melinda C Aldrich, Erin Kobetz, Consuelo H Wilkins

Abstract read
In one paragraph

Article in Journal of public health (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rohini ChakravarthyVanderbilt University School of Medicine, Nashville, TN, USA.ORCID 0000-0001-9640-8200
Sarah C StallingsDepartment of Medicine, Division of Geriatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Digna R Velez EdwardsDivision of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA.
Sifang Kathy ZhaoInstitute for Medicine and Public Health, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-9019-2186
Douglas ConwayVanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center, Nashville, TN, USA.
J Sunil RaoDepartment of Public Health Sciences, University of Miami School of Medicine, Miami, FL, USA.
Melinda C AldrichDepartment of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Erin KobetzDepartment of Public Health Sciences, University of Miami School of Medicine, Miami, FL, USA.
Consuelo H WilkinsDepartment of Medicine, Division of Geriatrics, Vanderbilt University Medical Center, Nashville, TN, USA.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Training and Mentoring CoreU54MD010722 · NIMHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI COX, NANCY J · 2016 to 2020
$11.9M
NCATS NIH HHS UL1 TR000445NIMHD NIH HHS U54 MD010722
6 · The paper itself

Abstract

backgroundCollecting social determinants of health in electronic health records is time-consuming. Meanwhile, an Area Deprivation Index (ADI) aggregates sociodemographic information from census data. The objective of this study was to ascertain whether ADI is associated with stage of human papillomavirus (HPV)-related cancer at diagnosis.

methodsWe tested for the association between the stage of HPV-related cancer presentation and ADI as well as the association between stage and the value of each census-based measure using ordered logistic regression, adjusting for age, race and sex.

resultsAmong 3247 cases of HPV-related cancers presenting to an urban academic medical center, the average age at diagnosis was 57. The average stage at diagnosis was Surveillance, Epidemiology and End Results Stage 3. In the study population, 43% of patients were female and 87% were white. In this study population, there was no association between stage of HPV-related cancer presentation and either aggregate or individual census variables.

conclusionsThese results may reflect insufficient sample size, a lack of socio-demographic diversity in our population, or suggest that simplifying social determinants of health into a single geocoded index is not a reliable surrogate for assessing a patient's risk for HPV-related cancer.

Indexed as

AlphapapillomavirusNeoplasmsPapillomavirus InfectionsCensusesFemaleHumansMalePapillomaviridaecancerracesocial determinants

Identifiers

PMID33512511
PMCPMC8904191

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.