ArticlePhysical review letters2021
Swirling Instability of the Microtubule Cytoskeleton.
Article in Physical review letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 49 citations in OpenAlex.
- Article
- Mechanochemical feedback between confinement and actin crosslinking drives the shape dynamics of liquid-like droplets.Nature communications · 2026Article
- Dynamic flow control through active matter programming language.Nature materials · 2025Article
- Evidence of universal conformal invariance in living biological matter.Nature physics · 2025Article
- Cytoplasmic stirring by active carpets.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Effect of fluid elasticity on the emergence of oscillations in an active elastic filament.Journal of the Royal Society, Interface · 2024Article
- Fly embryo nuclei riding on two-fluid flow.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Self-emergent vortex flow of microtubule and kinesin in cell-sized droplets under water/water phase separation.Communications chemistry · 2023Article
- Go with the flow - bulk transport by molecular motors.Journal of cell science · 2023Review
- A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli.Cell reports · 2022Article
- Active nematic order and dynamic lane formation of microtubules driven by membrane-bound diffusing motors.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Sustained enzymatic activity and flow in crowded protein droplets.Nature communications · 2021Article
- On the Role of Electrostatic Repulsion in Topological Defect-Driven Membrane Fission.Membranes · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
In the cellular phenomena of cytoplasmic streaming, molecular motors carrying cargo along a network of microtubules entrain the surrounding fluid. The piconewton forces produced by individual motors are sufficient to deform long microtubules, as are the collective fluid flows generated by many moving motors. Studies of streaming during oocyte development in the fruit fly Drosophila melanogaster have shown a transition from a spatially disordered cytoskeleton, supporting flows with only short-ranged correlations, to an ordered state with a cell-spanning vortical flow. To test the hypothesis that this transition is driven by fluid-structure interactions, we study a discrete-filament model and a coarse-grained continuum theory for motors moving on a deformable cytoskeleton, both of which are shown to exhibit a swirling instability to spontaneous large-scale rotational motion, as observed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.