ArticleChemical research in toxicology2021
Volatile Organic Compounds in Mainstream Smoke of Sixty Domestic Little Cigar Products.
Article in Chemical research in toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 32 citations in OpenAlex.
- Benzo[a]pyrene in the Mainstream Smoke of Little Cigars.Chemical research in toxicology · 2025Article
- Study on quality enhancement during cigar tobacco fermentation byFrontiers in microbiology · 2025Article
- Analyzing microbial community and volatile compound profiles in the fermentation of cigar tobacco leaves.Applied microbiology and biotechnology · 2024Article
- Geographical Origin Determination of Cigar at Different Spatial Scales Based on C and N Metabolites and Mineral Elements Combined with Chemometric Analysis.Biological trace element research · 2023Article
- Smoking is associated with elevated blood level of volatile organic compounds: a population-based analysis of NHANES 2017-2018.Archives of public health = Archives belges de sante publique · 2023Article
- Study on the correlation between the dominant microflora and the main flavor substances in the fermentation process of cigar tobacco leaves.Frontiers in microbiology · 2023Article
- Harmful and Potentially Harmful Constituents in the Filler and Smoke of Tobacco-Containing Tobacco Products.ACS omega · 2022Article
- Carcinogenic components of tobacco and tobacco smoke: A 2022 update.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022Review
- 1,3-Butadiene: a ubiquitous environmental mutagen and its associations with diseases.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2022Review
- Phyllosphere microbial community of cigar tobacco and its corresponding metabolites.Frontiers in microbiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
The mainstream smoke yields of five volatile organic compounds (VOCs) were determined from 60 commercial U.S. little cigar products under ISO 3308 and Canadian Intense (CI) smoking regimens on linear smoking machines using a gas sampling bag collection. The five VOCs, 1,3-butadiene, acrylonitrile, benzene, isoprene, and toluene were analyzed using an automated GC/MS analytical method validated for measuring various VOCs in mainstream smoke. The VOCs range in amounts from micrograms to milligrams per little cigar. VOC deliveries vary considerably among the little cigar products under the ISO smoking regimen primarily due to varying filter ventilation. Under the CI smoking regimen where filter ventilation is blocked, the delivery range narrows, although individual and total VOC yields are approximately 2 fold higher than those under the ISO smoking regimen. Correlation analysis reveals strong associations between acrylonitrile and 1,3-butadiene or toluene under the ISO smoking regimen. Compared to cigarettes, little cigars delivered substantially higher VOC mainstream smoke yields under both ISO and CI smoking regimens. Moreover, little cigar smoke also contains higher VOCs than cigarette smoke when adjusted for mass of tobacco.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.