Evidence map›Paper›PMID 33512067›Full record

ArticlePhysiological reports2021

TRPV4 channel activation induces the transition of venous and arterial endothelial cells toward a pro-inflammatory phenotype.

Kathia Beddek, Florent Raffin, Delphine Borgel, François Saller, Diane Riccobono, Régis Bobe, François-Xavier Boittin

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The role of TRPV4 in programmed cell deaths.Molecular biology reports · 2024
    Review
  8. Astrocytic TRPV4 Channels and Their Role in Brain Ischemia.International journal of molecular sciences · 2023
    Review
  9. Article
  10. Arbitrary CaFrontiers in pharmacology · 2022
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kathia BeddekINSERM Unité Mixte de Recherche-Santé 1176, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Florent RaffinDépartement des Plateformes, unité Analyses Biologiques, IRBA (Institut de Recherche Biomédicale des Armées), Brétigny-sur-Orge, France.
Delphine BorgelINSERM Unité Mixte de Recherche-Santé 1176, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
François SallerINSERM Unité Mixte de Recherche-Santé 1176, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Diane RiccobonoDépartement Effets Biologiques des Rayonnements, unité de Radiobiologie, IRBA (Institut de Recherche Biomédicale des Armées), Brétigny-sur-Orge, France.
Régis BobeINSERM Unité Mixte de Recherche-Santé 1176, Université Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
François-Xavier BoittinDépartement Effets Biologiques des Rayonnements, unité de Radiobiologie, IRBA (Institut de Recherche Biomédicale des Armées), Brétigny-sur-Orge, France.ORCID 0000-0003-2723-9858
Université Paris-Sud · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Transient Receptor Potential Vanilloid 4 (TRPV4) of endothelial cells contributes to many important functions including the regulation of Ca

Indexed as

Antigens, CDApoptosisCadherin 5CadherinsCalcium SignalingCells, CulturedElectric ImpedanceEndothelial CellsHumansHuman Umbilical Vein Endothelial CellsInflammation MediatorsIntercellular Adhesion Molecule-1LeucineNF-kappa BPermeabilityPhenotypeAntigens, CDCadherin 5CadherinsICAM1 protein, humanInflammation MediatorsIntercellular Adhesion Molecule-1LeucineN-(1-((4-(2-(((2,4-dichlorophenyl)sulfonyl)amino)-3-hydroxypropanoyl)-1-piperazinyl)carbonyl)-3-methylbutyl)-1-benzothiophene-2-carboxamideNF-kappa BSulfonamidesTRPV4 protein, humanTRPV Cation Channelsapoptosiscytoskeletonendothelial barrierendothelial cellsICAM-1TRPV4 channelVE-Cadherin

Identifiers

PMID33512067
PMCPMC7845413
OpenAlexW3124849501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.