ArticleThe British journal of dermatology2021
Perceived psychological stress and risk of herpes zoster: a nationwide population-based cohort study.
Article in The British journal of dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Risk factors for herpes zoster infections: a systematic review and meta-analysis unveiling common trends and heterogeneity patterns.Infection · 2024Pooled it
- Multiple Sclerosis and Viruses: « Liaisons Dangereuses ».Reviews in medical virology · 2026Review
- Increased neuro-ophthalmic manifestations of herpes zoster infection incidence: A 14-year cohort study from a tertiary medical center.Indian journal of ophthalmology · 2026Article
- Association of Chronic Diseases With Herpes Zoster in China: A Nationwide Population-Based Survey.Health care science · 2026Article
- Early-Onset Herpes Zoster in a 10-Month-Old Infant Following Nonvenomous Snake Exposure: A Rare Case Report.Clinical case reports · 2026Article
- Elevated Risk of Herpes Zoster in Vitiligo Patients: A Nationwide Population-Based Cohort Study of Taiwan.The Journal of dermatology · 2026Article
- Associations between leisure-time physical activity and sleep problems among 11 346 Danish adults: the moderating role of stress.European journal of public health · 2026Article
- Prevalence of herpes zoster in individuals who have received COVID-19 vaccine and/or had COVID-19: a cross-sectional study.BMC infectious diseases · 2026Article
- Integrated Western and Traditional Chinese Medicine Approaches for Herpes Zoster and Post-Herpetic Neuralgia: A Narrative Review.Drug design, development and therapy · 2026Review
- Article
- Epidemiology of herpes zoster at a tertiary care centre in Eastern India.Bioinformation · 2026Article
- Perceived Chronic Stress prior to SARS-CoV-2 Infection Predicts Ongoing Symptomatic COVID-19: A Prospective Cohort Study.Psychotherapy and psychosomatics · 2026Article
- The Risk of Herpes Zoster in Patients with Depressive Disorders: A German Claims Database Analysis.Infectious diseases and therapy · 2025Article
- 'Everyone has heard of it, but no one knows what it is': a qualitative study of patient understandings and experiences of herpes zoster.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Article
- Comparing the effectiveness of different vaccines in individuals with and without autoimmune diseases: a study protocol for a target trial emulation.Frontiers in public health · 2025Article
- Changing age pattern and diverse outcomes of herpes zoster ophthalmicus: exploring the temporal trend, decrease in incident age and influence of treatment strategies.International ophthalmology · 2024Article
- An unusual presentation of Herpes zoster and associated differentials.The Journal of the Canadian Chiropractic Association · 2024Article
- Trigeminal herpes zoster with multi-dermatome and temporomandibular joint involvement.Journal of dental sciences · 2024Article
- Multidermatomal herpes zoster triggered by psychological stress in an immunocompetent young adult: a rare case report and clinical insights.Annals of medicine and surgery (2012) · 2023Article
- Herpes Zoster Duplex Bilateralis After Trauma Induced Emotional Dysregulation: A Case Report and Literature Review.Infection and drug resistance · 2022Article
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPsychological stress may reduce cellular immunity, but its role in triggering latent infections, including herpes zoster (HZ), is controversial.
objectivesTo examine the association between perceived psychological stress and risk of HZ.
methodsIn a linked registry-based cohort study, we followed 77 310 persons aged 40 years or older who participated in the 2010 Danish National Health Survey from 1 May 2010 until HZ diagnosis, death, emigration or 1 July 2014, whichever occurred first. We computed hazard ratios (HRs) of HZ associated with Cohen's Perceived Stress Scale (PSS) score (range 0-40) using Cox regression with age as the timescale, adjusted for sex, immunosuppressive and selected chronic conditions, immunosuppressive drugs, and sociodemographic, lifestyle and anthropometric factors. The PSS measures chronic stress perceived by an individual in response to various demands of daily life. We modelled the PSS score using quintiles and a restricted cubic spline function.
resultsThe unadjusted rate of HZ varied from 5·53 to 7·20 per 1000 person-years from the lowest to the highest PSS score quintile. Compared with the lowest PSS score quintile, the adjusted HR for HZ was 1·00 [95% confidence interval (CI) 0·86-1·16], 1·08 (95% CI 0·92-1·26), 1·05 (95% CI 0·90-1·23) and 1·14 (95% CI 0·97-1·34) for the second to the fifth quintile, respectively. In cubic spline analyses, PSS scores < 20 were not associated with increased HR of HZ, but thereafter the HR increased linearly from 1·10 (95% CI 0·85-1·41) to 2·22 (95% CI 1·32-3·75).
conclusionsOur study indicated that high levels of psychological stress are associated with increased risk of HZ.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.