Evidence map›Paper›PMID 33511560›Full record

ArticleJournal of cell communication and signaling2021

Comparative stemness and differentiation of luminal and basal breast cancer stem cell type under glutamine-deprivation.

Heena Jariyal, Chanchal Gupta, Shambhavi Andhale, Sonali Gadge, Akshay Srivastava

Open access · greenAbstract read
In one paragraph

Article in Journal of cell communication and signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Heena JariyalDepartment of Biotechnology, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.ORCID http://orcid.org/0000-0003-0850-0221
Chanchal GuptaDepartment of Biotechnology, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.ORCID http://orcid.org/0000-0003-4587-0440
Shambhavi AndhaleDepartment of Biotechnology, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.ORCID http://orcid.org/0000-0002-6479-3041
Sonali GadgeDepartment of Biotechnology, National Institute of Pharmaceutical Education and Research-Ahmedabad, Gandhinagar, Gujarat, India.ORCID http://orcid.org/0000-0002-5425-9611
Akshay SrivastavaDepartment of Medical Devices, National Institute of Pharmaceutical Education and Research-Ahmedabad, Opposite Air force Station, Palaj, Gandhinagar, Gujarat, 382355, India. akshay.srivastava@niperahm.ac.in.ORCID http://orcid.org/0000-0001-5048-9420
National Institute of Pharmaceutical Education and Research (NIPER) - Ahmedabad · IN

Funding

Department of Biotechnology , Ministry of Science and Technology BT/HRD/35/02/2006Science and Engineering Research Board ECR/2016/002038
6 · The paper itself

Abstract

Glutamine (gln) metabolism has emerged as a cancer therapeutic target in past few years, however, the effect of gln-deprivation of bCSCs remains elusive in breast cancer. In this study, effect of glutamine on stemness and differentiation potential of bCSCs isolated from MCF-7 and MDAMB-231 were studied. We have shown that bCSCs differentiate into CD24

Indexed as

2‐Diazo‐norleucine (DON)Breast cancer stem cellsEpithelial mesenchymal transitionGlutamineβ-Catenin

Identifiers

PMID33511560
PMCPMC7991029
OpenAlexW3121875759

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.