ArticleJournal of patient-reported outcomes2021
Epilepsy and quality of life in Iranian epileptic patients.
Article in Journal of patient-reported outcomes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Lived experiences that influence the quality of life among patients with epilepsy at Mulago National Referral Hospital.Epilepsy & behavior reports · 2026Article
- Quality of Life Among Patients With Epilepsy in Jeddah, Saudi Arabia: A Descriptive Cross-Sectional Study.Nursing research and practice · 2026Article
- Factors Associated with Poor Health-Related Quality of Life Among Patients with Epilepsy at Mulago National Referral Hospital.Neuropsychiatric disease and treatment · 2026Article
- Quality of life among patients with epilepsy in the western region of KSA: A cross-sectional study.Journal of Taibah University Medical Sciences · 2025Article
- Quality of life, depression, daytime sleepiness and fatigue in Omani people with epilepsy: a cross-sectional study.BMC neurology · 2025Article
- Editorial: Epilepsy research in the developing countries: the neuro-ethical issues, cross-cultural differences, and relevance to comprehensive management.Frontiers in neurology · 2024Article
- Quality of Life among Patients with Epilepsy: Institutional-based Survey, Western Rajasthan, India.Annals of Indian Academy of NeurologyArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundEpilepsy is one of the most common neurological disorders with physical, emotional, and social consequences. Previous studies indicate that epilepsy symptoms can highly affect the epileptic patients' satisfaction in life. The aim of the present study is to investigate the QOL of People with Epilepsy (PWE) in Khorasan Razavi province, Iran.
methodsIn this study, 100 patients were randomly selected. After confirmation of the diagnosis of epilepsy by neurologists and fulfilling the entrance criteria, patients completed the Quality of Life in Epilepsy-31 inventory (QOLIE-31) questionnaire. Finally, data was analyzed statistically by SPSS software.
resultsThe study sample comprised 100 PWE, aged 18-74 years (34 ± 13), of whom 58 (58%) were females. Tonic-colonic seizure was the most common (60%) type of seizure. The obtained score of each subscale and the range of the QOLIE-31 total score was 16.40-79.18 with the mean of 50 (SD = 16). The energy-fatigue subscale score was significantly higher in patients younger than 35 (p = 0.018). The data analysis showed that the seizure worry subscale was significantly higher in single patients (p = 0.04). Duration of epilepsy had a positive correlation with QOLIE-31 total score (p = 0.038), and a negative relationship with energy-fatigue subscale (p = 0.018). In contrast with previous studies, which reported the frequency of the epileptic episodes as the most important predictor of QOL, our results showed no significant correlation between the number of the episodes and overall QOL score (p = 0.063). However, the number of episodes was significantly correlated with emotional well-being and cognition subscales. Furthermore, the results indicated that poor QOL score is correlated with depressed mood.
conclusionIn fact, the ultimate and preferred outcome of all treatments and care interventions is the patient's QOL. Thus, improvement of the QOL by means of obtaining more information about its contributing factors, in PWE should be one of the main goals in the patients' treatment.
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