ArticleJHEP reports : innovation in hepatology2021
Sex disparities in waitlisting and liver transplant for acute liver failure.
Article in JHEP reports : innovation in hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Addressing gender-based disparities in liver transplantation: A global analysis of surgical access and donor organ allocation.World journal of transplantation · 2026Article
- The Clinical Implications of Sex on Waitlist Outcomes in Patients With Acute-on-Chronic Liver Failure.Gastro hep advances · 2026Article
- Social Determinants Are Important Barriers to Completion of the Liver Transplant Pathway and Are Associated with Waitlisting and Mortality in Hepatocellular Carcinoma.Digestive diseases and sciences · 2026Article
- Sex-based disparities in liver transplantation: Evidence from a nationwide Italian cohort.JHEP reports : innovation in hepatology · 2025Article
- Trends in Liver Transplantation for Acute Liver Failure in a Spanish Multicenter Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- A Comprehensive Overview of the Past, Current, and Future Randomized Controlled Trials in Hepatic Encephalopathy.Medicina (Kaunas, Lithuania) · 2023Review
- [Sex-specific differences in gastroenterological diseases].Innere Medizin (Heidelberg, Germany) · 2023Review
- Prognostic Scores in Acute Liver Failure Due to Viral Hepatitis.Diagnostics (Basel, Switzerland) · 2023Review
- Sex Disparities in Outcome of Patients with Alcohol-Related Liver Cirrhosis within the Eurotransplant Network-A Competing Risk Analysis.Journal of clinical medicine · 2022Article
- Mortality and Causes of Death After Liver Transplantation: Analysis of Sex Differences in a Large Nationwide Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2022Article
- Celebrating the third year of JHEP Reports in the COVID-19 era.JHEP reports : innovation in hepatology · 2021Article
- Liver Transplantation for Acute Liver Failure- Indication, Prioritization, Timing, and Referral.Journal of clinical and experimental hepatologyReview
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
BACKGROUND &
aimsSex disparities in liver transplantation (LT) for chronic liver disease have been described. It is unclear if similar disparities exist for acute liver failure (ALF).
methodsAdults waitlisted for LT from 2002 to 2016 with ALF were investigated using the United Network of Organ Sharing database. Clinical characteristics and causative aetiologies were compared between men and women who were waitlisted Status-1. Differences in LT, waitlist removal, and 1-year post-transplant survival were explored.
resultsOf 8,408 patients waitlisted for LT with ALF, 41.3% of men and 63.9% of women were waitlisted Status-1 (
conclusionsWomen with ALF are more likely to be waitlisted Status-1 than men. There were no clear disparities in LT or waitlist removal. Sex differences in LT and waitlist removal were attenuated on fully adjusted models, suggesting that these disparities may in part be mitigated by Status-1 listing. LAY SUMMARY: Women with acute liver failure appear to be sicker than men and more often require urgent Status-1 waitlisting. There were no sex disparities in waitlist removal because of clinical deterioration or liver transplantation. This is in contrast to chronic liver disease, where sex disparities exist. The Status-1 waitlisting that women with acute liver failure receive may in part mitigate sex disparities in liver transplantation.
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