Evidence map›Paper›PMID 33511231›Full record

ArticleOpen forum infectious diseases2021

Risk Factors for Mortality, Intensive Care Unit Admission, and Bacteremia in Patients Suspected of Sepsis at the Emergency Department: A Prospective Cohort Study.

Valentino D'Onofrio, Agnes Meersman, Sara Vijgen, Reinoud Cartuyvels, Peter Messiaen, Inge C Gyssens

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Be-SNAP: the Belgian Sepsis National Action Plan.Frontiers in public health · 2025
    Article
  5. Review
  6. Urinary microRNAs in sepsis function as a novel prognostic marker.Experimental and therapeutic medicine · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Valentino D'OnofrioFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.ORCID 0000-0003-3828-044
Agnes MeersmanEmergency Department, Jessa Hospital, Hasselt, Belgium.
Sara VijgenClinical Laboratory, Jessa Hospital, Hasselt, Belgium.
Reinoud CartuyvelsClinical Laboratory, Jessa Hospital, Hasselt, Belgium.ORCID 0000-0003-0795-0191
Peter MessiaenFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.
Inge C GyssensFaculty of Medicine and Life Sciences, Hasselt University, Hasselt, Belgium.ORCID 0000-0002-9226-0752

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a clear need for a better assessment of independent risk factors for in-hospital mortality, intensive care unit admission, and bacteremia in patients presenting with suspected sepsis at the emergency department.

methodsA prospective observational cohort study including 1690 patients was performed. Two multivariable logistic regression models were used to identify independent risk factors.

resultsSequential organ failure assessment (SOFA) score of ≥2 and serum lactate of ≥2mmol/L were associated with all outcomes. Other independent risk factors were individual SOFA variables and systemic inflammatory response syndrome variables but varied per outcome. Mean arterial pressure <70 mmHg negatively impacted all outcomes.

conclusionsThese readily available measurements can help with early risk stratification and prediction of prognosis.

Indexed as

bacteremiaemergency departmentICU admissionrisk factorssepsis

Identifiers

PMID33511231
PMCPMC7813192

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.