ArticleEuropean thyroid journal2020
Microbiome and Graves' Orbitopathy.
Article in European thyroid journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- The relationship between thyroid and human-associated microbiota: A systematic review of reviews.Reviews in endocrine & metabolic disorders · 2024Pooled it
- The Broad Effect of Iodine in Graves' Hyperthyroidism and Its Relationship with the Gut Microbiota.Nutrients · 2026Review
- Unravelling the pathogenic mechanisms in Graves' orbitopathy.European thyroid journal · 2025Review
- Inflammatory Proteins Mediate the Effect of Gut Microbiota on Graves' Ophthalmopathy: A Mendelian Randomization Study.Translational vision science & technology · 2025Article
- The gut microbiota and its role in Graves' Disease: a systematic review and meta-analysis.Bioscience of microbiota, food and health · 2024Review
- Significance of thyroperoxidase and thyroglobulin antibodies in medically treated Graves' disease.European thyroid journal · 2023Article
- Graves' disease: moving forwards.Archives of disease in childhood · 2023Review
- Current concepts regarding Graves' orbitopathy.Journal of internal medicine · 2022Review
- Cellular and molecular basis of thyroid autoimmunity.European thyroid journal · 2022Review
- Probiotic Bifidobacterium longum supplied with methimazole improved the thyroid function of Graves' disease patients through the gut-thyroid axis.Communications biology · 2021Article
- Emerging Insights Into the Role of Epigenetics and Gut Microbiome in the Pathogenesis of Graves' Ophthalmopathy.Frontiers in endocrinology · 2021Review
- The Role of the Microbiota in Graves' Disease and Graves' Orbitopathy.Frontiers in cellular and infection microbiology · 2021Review
- Thinking inside the box: Current insights into targeting orbital tissue remodeling and inflammation in thyroid eye disease.Survey of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies from animal models of autoimmunity have highlighted the potential importance of microorganisms and their metabolic products in shaping the immune system. SUMMARY: This review provides an introduction to the current state-of-the-art in microbiome research both from the perspective of "what is known" and of methodologies for its investigation. It then summarises the evidence for a role for the microbiome in the pathogenesis of Graves' disease and Graves' orbitopathy with reference to animal models and studies in human cohorts, from both published and ongoing sources. KEY MESSAGE: Microbiome research is in its infancy but has already provided novel insights into disease pathogenesis across the spectrum from cancer to mental health and autoimmunity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.