Evidence map›Paper›PMID 33511056›Full record

ArticleJournal of traditional and complementary medicine2021

Cytoarchitectural improvement in Leydig cells of diabetic rats after treatment with aqueous and ethanol extracts of

Modeste Wankeu-Nya, Adrian Florea, Ştefana Bâlici, Horea Matei, Pierre Watcho, Albert Kamanyi

Open access · diamondAbstract read
In one paragraph

Article in Journal of traditional and complementary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Modeste Wankeu-NyaAnimal Organisms Biology and Physiology Laboratory, Faculty of Science, University of Douala, P.O. BOX, 24157, Douala, Cameroon.
Adrian FloreaDepartment of Cell and Molecular Biology, Faculty of Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 6 L. Pasteur St, Cluj-Napoca, 400359, Romania.
Ştefana BâliciDepartment of Cell and Molecular Biology, Faculty of Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 6 L. Pasteur St, Cluj-Napoca, 400359, Romania.
Horea MateiDepartment of Cell and Molecular Biology, Faculty of Medicine, "Iuliu Haţieganu" University of Medicine and Pharmacy, 6 L. Pasteur St, Cluj-Napoca, 400359, Romania.
Pierre WatchoAnimal Physiology and Phytopharmacology Laboratory, University of Dschang, P.O. BOX 67, Dschang, Cameroon.
Albert KamanyiAnimal Physiology and Phytopharmacology Laboratory, University of Dschang, P.O. BOX 67, Dschang, Cameroon.
Iuliu Hațieganu University of Medicine and Pharmacy · ROUniversité de Dschang · CMUniversity of Douala · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimRecent studies have demonstrated the androgenic effects of EXPERIMENTAL PROCEDURE: Besides a normal group, 4 groups of diabetic rats were treated orally with Millipore water (10 ml/kg, diabetic), sildenafil citrate (1.44 mg/kg), aqueous (500 mg/kg) and ethanol (100 mg/kg) extracts of RESULTS AND

conclusionThe ultrastructure of LCs in control rats was normal, while that in diabetic rats exhibited large heterochromatization in the nuclei, reduced amount of smooth endoplasmic reticulum with no lipid droplets in the cytoplasm, many autophagosomes and degenerated mitochondria containing lots of electron dense granules in the matrix. Interestingly, treatment with

Indexed as

AutophagyElectron microscopyInterstitial cellsPhytomedicineStreptozotocin

Identifiers

PMID33511056
PMCPMC7817706
OpenAlexW2973700972

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.