ArticlePulmonary medicine2021
Association of Vitamin D Deficiency and Newly Diagnosed Pulmonary Tuberculosis.
Article in Pulmonary medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Association of variant vitamin statuses and tuberculosis development: a systematic review and meta-analysis.Annals of medicine · 2024Pooled it
- Paradoxical hypercalcemia in tuberculosis with concurrent vitamin D deficiency: mechanisms, clinical implications, and management strategies.Annals of medicine and surgery (2012) · 2026Review
- Efficacy ofFrontiers in medicine · 2026Article
- Rickets, Vitamin D Deficiency and Tuberculosis in Children of St. Petersburg and its Region.The open respiratory medicine journal · 2026Article
- Search for Disease-Specific Genetic Markers Originated from the Vitamin D Binding Protein Gene Polymorphisms in the Multiple Sclerosis Cohort in the Latvian Population.International journal of molecular sciences · 2025Article
- Nutritional Factors and Food and Nutrition Insecurity in Patients with Tuberculosis.Nutrients · 2025Article
- Comparative Study of Vitamin D Levels in Newly Diagnosed Tuberculosis and a Normal Population.Medicina (Kaunas, Lithuania) · 2024Article
- The impact of meteorological factors on tuberculosis incidence in Spain: a spatiotemporal analysis.Epidemiology and infection · 2024Article
- An investigation of the correlation of vitamin D status and management outcomes in patients with severe COVID-19 at a South African tertiary hospital.IJID regions · 2023Article
- Association of circulating serum free bioavailable and total vitamin D with cathelicidin levels among active TB patients and household contacts.Scientific reports · 2023Article
- Severe Vitamin D Deficiency as a Risk Factor in Newly Diagnosed Tuberculosis Patients: Comparative Study on Inhabitants of High Altitude Region.International journal of preventive medicine · 2023Article
- Hypovitaminosis D among newly diagnosed pulmonary TB patients and their household contacts in Uganda.Scientific reports · 2022Article
- Respiratory Tract Infections in Diabetes - Lessons From Tuberculosis and Influenza to Guide Understanding of COVID-19 Severity.Frontiers in endocrinology · 2022Review
- Association of Vitamin D Deficiency With Pulmonary Tuberculosis: A Systematic Review and Meta-Analysis.Cureus · 2021Review
- Vitamin D, Thyroid Hormones and Cardiovascular Risk: Exploring the Components of This Novel Disease Triangle.Frontiers in physiology · 2021Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionVitamin D has a significant role in host immune defense against Mycobacterium tuberculosis. It has been suggested that pulmonary tuberculosis may be associated with lower levels of vitamin D. Present study was therefore undertaken to identify the association between vitamin D deficiency and pulmonary tuberculosis.
methodsA case-control study was conducted in a tertiary care hospital from 2014 to 2016, including 50 adult newly diagnosed sputum positive pulmonary tuberculosis patients as cases and 50 age and sex-matched healthy participants as control groups. All participants in the study group had undergone detailed clinical examination and routine laboratory investigations, including vitamin D, calcium, and sputum for AFB. The clinical characteristics, X-ray findings, sputum AFB, and vitamin D levels were analyzed and compared with data obtained from healthy controls.
resultsIn both groups, the majority were men (88%). BMI was significantly (<0.0001∗) lower in the tuberculosis group (19.40 (17.20, 22.0) vs. 24.00 (22.50, 25.47)). Serum vitamin D levels were significantly lower (
conclusionThe prevalence of vitamin D deficiency in pulmonary tuberculosis cases is very high. Hypovitaminosis D was associated with more severe clinical symptoms, higher sputum smear positivity, and extensive lesions in chest radiograph among pulmonary tuberculosis patients.
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