ArticleRespirology case reports2021
Lung cancer presenting as an acute appendicitis.
Article in Respirology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- Acute Appendicitis Caused by Metastasis from Other Organs: A Systematic Review.Journal of gastrointestinal cancer · 2024Pooled it
- Clinical Manifestations and Outcomes of Lung Cancer Patients With Appendiceal Metastasis.Thoracic cancer · 2026Review
- Acute Appendicitis due to Rare Metastasis From Lung Cancer: A Case Report.Respirology case reports · 2025Article
- Appendicitis while on alectinib for non-small cell lung cancer: a tale of two case reports.Frontiers in oncology · 2024Article
- Metastatic small cell lung cancer presenting as acute appendicitis: a case report.Journal of surgical case reports · 2023Article
- Lung cancer presenting as an acute appendicitis.Respirology case reports · 2021Article
- A Unique Presentation of Metastatic Gallbladder Carcinoma.Case reports in surgery · 2021Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Appendiceal metastasis is a rare complication of primary lung cancer and an extremely rare cause of appendicitis. We present the case of a 62-year-old male who presented with right lower quadrant abdominal pain which revealed not only appendiceal inflammation, but also a lung mass and mediastinal lymph nodes. He then proceeded to appendicectomy and two days post-operatively an endobronchial ultrasound-guided biopsy. His mediastinal lymph node biopsy revealed a lung adenocarcinoma and his subsequent appendiceal immunohistochemistry revealed the same staining pattern for thyroid transcription factor 1 (TTF-1) and cytokeratin 7 (CK-7). We conducted a literature review which revealed 12 previous case reports of lung metastasis to the appendix causing appendicitis including three patients in whom appendicitis was the presenting complaint leading to lung cancer diagnosis. This case highlights the diversity of presentations for patients suffering from metastatic lung cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.