Evidence map›Paper›PMID 33510894›Full record

ArticleClinical & translational immunology2021

Rheumatoid arthritis CD14

Trudy McGarry, Megan M Hanlon, Viviana Marzaioli, Clare C Cunningham, Vinod Krishna, Kieran Murray, Conor Hurson, Phil Gallagher, Sunil Nagpal, Douglas J Veale and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical & translational immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. JAK/STAT inhibition reprograms T cell activation and metabolism in inflammatory arthritis patients.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. [Role of Trained Immunity in the Association Between Periodontitis and Rheumatoid Arthritis].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. KK2DP7 Stimulates CD11bAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Trudy McGarryMolecular Rheumatology Trinity Biomedical Sciences Institute Trinity College Dublin Dublin Ireland.
Megan M HanlonMolecular Rheumatology Trinity Biomedical Sciences Institute Trinity College Dublin Dublin Ireland.
Viviana MarzaioliMolecular Rheumatology Trinity Biomedical Sciences Institute Trinity College Dublin Dublin Ireland.
Clare C CunninghamMolecular Rheumatology Trinity Biomedical Sciences Institute Trinity College Dublin Dublin Ireland.
Vinod KrishnaJanssen Research & Development, Immunology Spring House, PA Titusville New Jersey USA.
Kieran MurrayEULAR Centre of Excellence for Rheumatology Centre for Arthritis and Rheumatic Diseases St Vincent's University Hospital University College Dublin Dublin Ireland.
Conor HursonDepartment of Orthopaedics St Vincent's University Hospital UCD Dublin Ireland.
Phil GallagherEULAR Centre of Excellence for Rheumatology Centre for Arthritis and Rheumatic Diseases St Vincent's University Hospital University College Dublin Dublin Ireland.
Sunil NagpalJanssen Research & Development, Immunology Spring House, PA Titusville New Jersey USA.
Douglas J VealeEULAR Centre of Excellence for Rheumatology Centre for Arthritis and Rheumatic Diseases St Vincent's University Hospital University College Dublin Dublin Ireland.
Ursula FearonMolecular Rheumatology Trinity Biomedical Sciences Institute Trinity College Dublin Dublin Ireland.
St. Vincent's University Hospital · IETrinity College Dublin · IEJanssen (United States) · USUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study investigates the metabolic activity of circulating monocytes and their impact on pro-inflammatory responses in RA and explores whether this phenotype is already primed for inflammation before clinical manifestations of disease.

methodsBlood was collected and CD14

resultsCD14

conclusionRA CD14

Indexed as

arthralgiaimmunometabolismmonocytesrheumatoid arthritisSTAT3

Identifiers

PMID33510894
PMCPMC7815439
OpenAlexW3121154220

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.