Evidence map›Paper›PMID 33510814›Full record

ArticleOncology letters2021

Chemopreventive effect of 4'-hydroxychalcone on intestinal tumorigenesis in

Qing Chen, Jiahong Lei, Jinzhe Zhou, Shaoze Ma, Qi Huang, Bujun Ge

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. 4-Hydroxychalcone attenuates AngII-induced cardiac remodeling and dysfunction via regulating PI3K/AKT pathway.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qing ChenDepartment of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, P.R. China.
Jiahong LeiKey Laboratory of Birth Defects and Related Diseases of Women and Children, Department of Pediatrics, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
Jinzhe ZhouDepartment of General Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, P.R. China.
Shaoze MaDepartment of General Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, P.R. China.
Qi HuangDepartment of General Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, P.R. China.
Bujun GeDepartment of General Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai 200065, P.R. China.
Tongji University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chalcones and its derivatives are reported to exhibit anti-cancer effects in several cancer cell lines, including colon cancer cells. However, the

Indexed as

adenomatous polyposis colichalcone derivativeschemopreventioncolorectal cancerβ-catenin

Identifiers

PMID33510814
PMCPMC7836395
OpenAlexW3123665263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.