Evidence map›Paper›PMID 33510680›Full record

ArticleFrontiers in psychology2020

Early Life Stress Predicts Depressive Symptoms in Adolescents During the COVID-19 Pandemic: The Mediating Role of Perceived Stress.

Ian H Gotlib, Lauren R Borchers, Rajpreet Chahal, Anthony J Gifuni, Giana I Teresi, Tiffany C Ho

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Childhood Trauma, Perceived Stress, and Developmental Trajectories of Sleep Problems in Adolescents.Stress and health : journal of the International Society for the Investigation of Stress · 2026
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  9. Adversity and Risk of Adolescent Mental Health Admission During COVID-19.Stress and health : journal of the International Society for the Investigation of Stress · 2025
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  17. The Impact of the COVID-19 Pandemic on the Severity of Alcohol Use Disorder: Significance of Dual Disorders.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ian H GotlibDepartment of Psychology, Stanford University, Stanford, CA, United States.
Lauren R BorchersDepartment of Psychology, Stanford University, Stanford, CA, United States.
Rajpreet ChahalDepartment of Psychology, Stanford University, Stanford, CA, United States.
Anthony J GifuniDepartment of Psychology, Stanford University, Stanford, CA, United States.
Giana I TeresiDepartment of Psychology, Stanford University, Stanford, CA, United States.
Tiffany C HoDepartment of Psychiatry, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, United States.
Stanford University · USDouglas Mental Health University Institute · CAUniversity of California, San Francisco · US

Funding

Psychobiological Mechanisms Underlying the Association Between Early Life Stress and Depression Across AdolescenceR37MH101495 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB · 2018 to 2026
$6.6M
The Roles of Inflammatory and Glutamatergic Processes in the Neurodevelopmental Mechanisms Underlying Adolescent DepressionK01MH117442 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HO, TIFFANY CHEING · 2018 to 2022
$881k
The Effects of Early Life Stress on the Development of Brain Networks: Predicting Risk for Depression and Suicidal Ideation in AdolescenceF32MH120975 · NIMH · STANFORD UNIVERSITY · PI CHAHAL, RAJPREET · 2020 to 2022
$126k
NIMH NIH HHS F32 MH120975NIMH NIH HHS K01 MH117442NIMH NIH HHS R37 MH101495
6 · The paper itself

Abstract

backgroundExposure to early life stress (ELS) is alarmingly prevalent and has been linked to the high rates of depression documented in adolescence. Researchers have theorized that ELS may increase adolescents' vulnerability or reactivity to the effects of subsequent stressors, placing them at higher risk for developing symptoms of depression.

methodsWe tested this formulation in a longitudinal study by assessing levels of stress and depression during the COVID-19 pandemic in a sample of adolescents from the San Francisco Bay Area (

resultsAs expected, severity of ELS predicted levels of depressive symptoms during the pandemic [

conclusionsThese findings underscore the importance of monitoring the mental health of vulnerable children and adolescents during this pandemic and targeting perceived stress in high-risk youth.

Indexed as

adolescenceCOVID-19depressionearly life stressperceived stress

Identifiers

PMID33510680
PMCPMC7835338
OpenAlexW3091083257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.