Evidence map›Paper›PMID 33510308›Full record

ArticleScientific reports2021

Correlation of surface-enhanced Raman spectroscopic fingerprints of kidney transplant recipient urine with kidney function parameters.

Zhongli Huang, Shijian Feng, Qiunong Guan, Tao Lin, Jianhua Zhao, Christopher Y C Nguan, Haishan Zeng, David Harriman, Hong Li, Caigan Du

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Zhongli Huang *Department of Urology, Institute of Urology, Organ Transplantation Center, West China Hospital, Sichuan University, 37 Guoxuexiang, Chengdu, 610041, China.
Shijian Feng *Department of Urology, Institute of Urology, Organ Transplantation Center, West China Hospital, Sichuan University, 37 Guoxuexiang, Chengdu, 610041, China.
Qiunong GuanDepartment of Urologic Sciences, University of British Columbia, 2660 Oak Street, Vancouver, BC, V6H 3Z6, Canada.
Tao LinDepartment of Urology, Institute of Urology, Organ Transplantation Center, West China Hospital, Sichuan University, 37 Guoxuexiang, Chengdu, 610041, China.
Jianhua ZhaoImaging Unit, Integrative Oncology Department, BC Cancer Research Center, 675 W 10th Ave, Vancouver, BC, V5Z 1L3, Canada.
Christopher Y C NguanDepartment of Urologic Sciences, University of British Columbia, 2660 Oak Street, Vancouver, BC, V6H 3Z6, Canada.
Haishan ZengImaging Unit, Integrative Oncology Department, BC Cancer Research Center, 675 W 10th Ave, Vancouver, BC, V5Z 1L3, Canada.
David HarrimanDepartment of Urologic Sciences, University of British Columbia, 2660 Oak Street, Vancouver, BC, V6H 3Z6, Canada.
Hong LiDepartment of Urology, Institute of Urology, Organ Transplantation Center, West China Hospital, Sichuan University, 37 Guoxuexiang, Chengdu, 610041, China. lihongurology@163.com.
Caigan DuDepartment of Urologic Sciences, University of British Columbia, 2660 Oak Street, Vancouver, BC, V6H 3Z6, Canada. caigan.du@ubc.ca.
University of British Columbia · CASichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Routine monitoring of kidney transplant function is required for the standard care in post-transplantation management, including frequent measurements of serum creatinine with or without kidney biopsy. However, the invasiveness of these methods with potential for clinically significant complications makes them less than ideal. The objective of this study was to develop a non-invasive tool to monitor the kidney transplant function by using Surface-Enhanced Raman Spectroscopy (SERS). Urine and blood samples were collected from kidney transplant recipients after surgery. Silver nanoparticle-based SERS spectra of the urine were measured and evaluated using partial least squires (PLS) analysis. The SERS spectra were compared with conventional chemical markers of kidney transplant function to assess its predictive ability. A total of 110 kidney transplant recipients were included in this study. PLS results showed significant correlation with urine protein (R

Indexed as

Kidney TransplantationSpectrum Analysis, RamanTransplant RecipientsUrinalysisAdultBiomarkersFemaleHumansKidneyKidney Function TestsLeast-Squares AnalysisMaleVibrationBiomarkers

Identifiers

PMID33510308
PMCPMC7843595
OpenAlexW3123684218

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.