Evidence map›Paper›PMID 33510292›Full record

ArticleScientific reports2021

Cardiac hypoxic resistance and decreasing lactate during maximum apnea in elite breath hold divers.

Thomas Kjeld, Jakob Møller, Kristian Fogh, Egon Godthaab Hansen, Henrik Christian Arendrup, Anders Brenøe Isbrand, Bo Zerahn, Jens Højberg, Ellen Ostenfeld, Henrik Thomsen and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Thomas KjeldDepartment of Radiology, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark. thomaskjeld@dadlnet.dk.
Jakob MøllerDepartment of Radiology, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.ORCID http://orcid.org/0000-0001-6576-6494
Kristian FoghDepartment of Radiology, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.
Egon Godthaab HansenDepartment of Anesthesiology, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Henrik Christian ArendrupDepartment of Cardiothoracic Surgery, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Anders Brenøe IsbrandDepartment of Clinical Physiology and Nuclear Medicine, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Bo ZerahnDepartment of Clinical Physiology and Nuclear Medicine, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark.
Jens HøjbergDepartment of Cardiothoracic Anesthesiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Ellen OstenfeldDepartment of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
Henrik ThomsenDepartment of Radiology, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark.
Lars Christian GormsenDepartment of Nuclear Medicine & PET Centre, Aarhus University Hospital, Aarhus, Denmark.ORCID http://orcid.org/0000-0002-0144-1305
Marcus CarlssonDepartment of Clinical Sciences Lund, Lund University, Skåne University Hospital, Lund, Sweden.
University of Copenhagen · DKHerlev Hospital · DKLund University · SEAarhus University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breath-hold divers (BHD) enduring apnea for more than 4 min are characterized by resistance to release of reactive oxygen species, reduced sensitivity to hypoxia, and low mitochondrial oxygen consumption in their skeletal muscles similar to northern elephant seals. The muscles and myocardium of harbor seals also exhibit metabolic adaptations including increased cardiac lactate-dehydrogenase-activity, exceeding their hypoxic limit. We hypothesized that the myocardium of BHD possesses similar adaptive mechanisms. During maximum apnea

Indexed as

Adaptation, PhysiologicalBreath HoldingDivingAdultApneaBlood Gas AnalysisBlood PressureFemaleHeart RateHemodynamicsHumansHypoxiaMagnetic Resonance ImagingMaleMiddle AgedMyocardium

Identifiers

PMID33510292
PMCPMC7844051
OpenAlexW3125983687

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.