Evidence map›Paper›PMID 33510088›Full record

ArticleNeural regeneration research2021

Mitochonic acid 5 regulates mitofusin 2 to protect microglia.

Jian Tan, Shuang-Xi Chen, Qing-Yun Lei, Shan-Qing Yi, Na Wu, Yi-Lin Wang, Zi-Jian Xiao, Heng Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jian TanDepartment of Neurology, The First Affiliated Hospital of University of South China, Hengyang, Hunan Province, China.
Shuang-Xi ChenDepartment of Neurology, The First Affiliated Hospital of University of South China, Hengyang, Hunan Province, China.
Qing-Yun LeiDepartment of Neurology, The First Affiliated Hospital of University of South China, Hengyang, Hunan Province, China.
Shan-Qing YiDepartment of Neurology, The First Affiliated Hospital of University of South China, Hengyang, Hunan Province, China.
Na WuDepartment of Neurology, The First Affiliated Hospital of University of South China, Hengyang, Hunan Province, China.
Yi-Lin WangDepartment of Neurology, The First Affiliated Hospital of University of South China, Hengyang, Hunan Province, China.
Zi-Jian XiaoDepartment of Neurology, The First Affiliated Hospital of University of South China, Hengyang, Hunan Province, China.
Heng WuDepartment of Neurology, The First Affiliated Hospital of University of South China, Hengyang, Hunan Province, China.
First Affiliated Hospital of University of South China · CNUniversity of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microglial apoptosis is associated with neuroinflammation and no effective strategies are currently available to protect microglia against inflammation-induced apoptosis. Mouse microglial BV-2 cells (5 × 10

Indexed as

apoptosisautophagy related 5Beclin1BV-2 cellscaspase-3inflammationlipopolysaccharidemitophagySmacsurvival

Identifiers

PMID33510088
PMCPMC8328753
OpenAlexW3122908320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.