Evidence map›Paper›PMID 33510062›Full record

ReviewNeural regeneration research2021

Promising drug targets and associated therapeutic interventions in Parkinson's disease.

Sachchida Nand Rai, Payal Singh, Ritu Varshney, Vivek K Chaturvedi, Emanuel Vamanu, M P Singh, Brijesh Kumar Singh

Open access · goldAbstract readReview
In one paragraph

Review in Neural regeneration research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Article
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  7. Review
  8. Article
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  11. Article
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  14. Article
  15. Review
  16. Modeling neurodegenerative and neurodevelopmental disorders in theLearning & memory (Cold Spring Harbor, N.Y.) · 2024
    Review
  17. Metformin role in Parkinson's disease: a double-sword effect.Molecular and cellular biochemistry · 2024
    Review
  18. Research Progress of Bioactive Components inMolecules (Basel, Switzerland) · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Sachchida Nand RaiCentre of Biotechnology, University of Allahabad, Prayagraj, India.
Payal SinghDepartment of Zoology, Institute of Science, Banaras Hindu University, Varanasi, India.
Ritu VarshneyDepartment of Bioengineering and Chemistry, Indian Institute of Technology Gandhinagar, Palaj, Gujarat, India.
Vivek K ChaturvediCentre of Biotechnology, University of Allahabad, Prayagraj, India.
Emanuel VamanuFaculty of Biotechnology, University of Agronomic Science and Veterinary Medicine, Bucharest, Romania.
M P SinghCentre of Biotechnology, University of Allahabad, Prayagraj, India.
Brijesh Kumar SinghDepartment of Pathology and Cell Biology, Columbia University Medical Center, New York, NY, USA.
University of Allahabad · INColumbia University Irving Medical Center · USIndian Institute of Technology Gandhinagar · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is one of the most debilitating brain diseases. Despite the availability of symptomatic treatments, response towards the health of PD patients remains scarce. To fulfil the medical needs of the PD patients, an efficacious and etiological treatment is required. In this review, we have compiled the information covering limitations of current therapeutic options in PD, novel drug targets for PD, and finally, the role of some critical beneficial natural products to control the progression of PD.

Indexed as

dopamineepigeneticsgene therapiesglutamate receptorlevodopamolecular chaperonesmonoamine oxidase Bmucuna alpha-synucleinParkinson’s diseasestriatumsubstantia nigra

Identifiers

PMID33510062
PMCPMC8328771
OpenAlexW3122457631

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.