Evidence map›Paper›PMID 33509935›Full record

Trial reportBMJ open diabetes research & care2021

Time spent in hypoglycemia is comparable when the same amount of exercise is performed 5 or 2 days weekly: a randomized crossover study in people with type 1 diabetes.

Isabelle Isa Kristin Steineck, Ajenthen G Ranjan, Signe Schmidt, Kirsten Norgaard

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open diabetes research & care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04089462 (Effects of Frequency and Duration of Exercise in People With Type 1 Diabetes - A Randomized Crossover Study), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04089462 nacompletednot on this map

Effects of Frequency and Duration of Exercise in People With Type 1 Diabetes - A Randomized Crossover Study

TypeinterventionalSponsorSteno Diabetes Center CopenhagenRan2019 to 2021Enrolled26ConditionsDiabetes Mellitus, Type 1, Insulin HypoglycemiaArms"Five sessions per period" - "Two sessions per period", "Two sessions per period" - "Five sessions per period"
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Isabelle Isa Kristin SteineckDiabetes Technology, Steno Diabetes Center Copenhagen, Gentofte, Denmark Isabelle.Steineck@iname.com.ORCID 0000-0001-5557-0885
Ajenthen G RanjanDiabetes Technology, Steno Diabetes Center Copenhagen, Gentofte, Denmark.
Signe SchmidtDiabetes Technology, Steno Diabetes Center Copenhagen, Gentofte, Denmark.
Kirsten NorgaardDiabetes Technology, Steno Diabetes Center Copenhagen, Gentofte, Denmark.
Steno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeople with type 1 diabetes are recommended to exercise regularly. However, limited evidence exists on how frequency and duration of exercise affect the risk of hypoglycemia. The study aimed to compare the percentage of time spent in hypoglycemia between two 5-day periods with different frequency and duration of physical activity. RESEARCH DESIGN AND

methodsIn this outpatient randomized crossover study, 26 participants aged 18-65 years with type 1 diabetes for ≥2 years and insulin pump use for ≥1 year were included. After a 7-day observation period, participants completed two 5-day intervention periods separated by a washout period of at least 14 days. One period included five exercise sessions on 5 consecutive days (5S), each consisting of 4 min of resistance training and 30 min of aerobic exercise. Another period included two exercise sessions on 2 days with at least 2 days in between (2S), each consisting of 10 min of resistance training and 75 min of aerobic exercise. During each period, participants performed in total 150 min of aerobic exercise and 20 min of resistance training and wore continuous glucose monitors (Dexcom G6) and accelerometers (ActiGraph wGT3X-BT).

resultsTwenty insulin pump-treated adults (10 women) with type 1 diabetes completed the study. The baseline median (range) age was 48 (24-64) years, glycated hemoglobin 55 (44-66) mmol/mol, diabetes duration 24 (8-57) years, and body mass index 28.4 (22.3-35.8) kg/m

conclusionsTime spent in hypoglycemia was comparable between the two 5-day periods with different duration and frequency of physical activity. TRIAL REGISTRATION NUMBER: NCT04089462.

Indexed as

Diabetes Mellitus, Type 1HypoglycemiaAdolescentAdultAgedCross-Over StudiesExerciseFemaleHumansHypoglycemic AgentsMaleMiddle AgedYoung AdultHypoglycemic Agentsdiabetes mellitusexercisehypoglycemiatype 1

Identifiers

PMID33509935
PMCPMC7845672
OpenAlexW3122333951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.