Evidence map›Paper›PMID 33509793›Full record

ArticleArchives of disease in childhood2021

Caring for critically ill adults in paediatric intensive care units in England during the COVID-19 pandemic: planning, implementation and lessons for the future.

Ruchi Sinha, Angela Aramburo, Akash Deep, Emma-Jane Bould, Hannah L Buckley, Elizabeth S Draper, Richard Feltbower, Rebecca Mitting, Sarah Mahoney, John Alexander and 6 more

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of disease in childhood, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Pediatric critical care capacity in Canada.Paediatrics & child health · 2025
    Article
  5. Article
  6. The care of critically ill adults with COVID-19 in Ontario pediatric intensive care units.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Response.Chest · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Nursing-Sensitive Outcomes among Patients Cared for in Paediatric Intensive Care Units: A Scoping Review.International journal of environmental research and public health · 2021
    Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Ruchi SinhaDepartment of Paediatric Intensive Care, Division of Women and Children's Services, Imperial College Healthcare NHS Trust, London, UK.
Angela AramburoPaediatric Intensive Care Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK.
Akash DeepPaediatric Intensive Care Unit, King's College Hospital NHS Foundation Trust, London, UK.
Emma-Jane BouldPaediatric Intensive Care Unit, Barts Health NHS Trust, London, UK.
Hannah L BuckleyPICANet, School of Medicine, University of Leeds, Leeds, UK.
Elizabeth S DraperHealth Sciences, University of Leicester, Leicester, UK.ORCID 0000-0001-9340-8176
Richard FeltbowerDivision of Epidemiology, University of Leeds, Leeds, UK.
Rebecca MittingDepartment of Paediatric Intensive Care, Division of Women and Children's Services, Imperial College Healthcare NHS Trust, London, UK.
Sarah MahoneyPaediatric Intensive Care Unit, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
John AlexanderPaediatric Intensive Care Unit, University Hospitals of North Midlands NHS Trust, Stoke-on-Trent, UK.
Stephen PlayforPICU, Royal Manchester Children's Hospital, Manchester, UK.
Amy Chan-DominyPaediatric Intensive Care Unit, Royal Brompton and Harefield NHS Foundation Trust, London, UK.ORCID 0000-0002-4161-1065
Simon NadelDepartment of Paediatric Intensive Care, Division of Women and Children's Services, Imperial College Healthcare NHS Trust, London, UK.
Ganesh SuntharalingamAdult Intensive Care Unit, North West London Hospitals NHS Trust, Harrow, UK.
James FraserPaediatric Intensive Care Unit, Bristol Royal Hospital for Children, Bristol, UK.
Padmanabhan RamnarayanDepartment of Paediatric Intensive Care, Division of Women and Children's Services, Imperial College Healthcare NHS Trust, London, UK p.ramnarayan@gosh.nhs.uk.ORCID 0000-0003-0784-8154

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the experience of paediatric intensive care units (PICUs) in England that repurposed their units, equipment and staff to care for critically ill adults during the first wave of the COVID-19 pandemic.

designDescriptive study.

settingSeven PICUs in England.

main outcome measures(1) Modelling using historical Paediatric Intensive Care Audit Network data; (2) space, staff, equipment, clinical care, communication and governance considerations during repurposing of PICUs; (3) characteristics, interventions and outcomes of adults cared for in repurposed PICUs.

resultsSeven English PICUs, accounting for 137 beds, repurposed their space, staff and equipment to admit critically ill adults. Neighbouring PICUs increased their bed capacity to maintain overall bed numbers for children, which was informed by historical data modelling (median 280-307 PICU beds were required in England from March to June). A total of 145 adult patients (median age 50-62 years) were cared for in repurposed PICUs (1553 bed-days). The vast majority of patients had COVID-19 (109/145, 75%); the majority required invasive ventilation (91/109, 85%). Nearly, a third of patients (42/145, 29%) underwent a tracheostomy. Renal replacement therapy was provided in 20/145 (14%) patients. Twenty adults died in PICU (14%).

conclusionIn a rapid and unprecedented effort during the first wave of the COVID-19 pandemic, seven PICUs in England were repurposed to care for adult patients. The success of this effort was underpinned by extensive local preparation, close collaboration with adult intensivists and careful national planning to safeguard paediatric critical care capacity.

Indexed as

AdultChildCOVID-19Critical CareEnglandForecastingHealth Plan ImplementationHumansIntensive Care Units, Pediatricepidemiologymicrobiology

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.