Evidence map›Paper›PMID 33509629›Full record

ReviewFertility and sterility2021

The impact of SARS-CoV-2 and COVID-19 on male reproduction and men's health.

Darshan P Patel, Nahid Punjani, Jingtao Guo, Joseph P Alukal, Philip S Li, James M Hotaling

Open access · bronzeAbstract readReview
In one paragraph

Review in Fertility and sterility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Sex differences in the cardiac stress response following SARS-CoV-2 infection of ferrets.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  9. SARS-CoV-2 and male infertility: from short- to long-term impacts.Journal of endocrinological investigation · 2023
    Review
  10. Spatial Distribution of SARS-CoV-2 Receptors and Proteases in Testicular Cells.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2023
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Animal models for COVID-19: advances, gaps and perspectives.Signal transduction and targeted therapy · 2022
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Darshan P PatelDivision of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah.
Nahid PunjaniCenter for Male Reproductive Medicine and Microsurgery, Department of Urology, Weill Cornell Medicine of Cornell University, New York, New York.
Jingtao GuoDivision of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah.
Joseph P AlukalDepartment of Urology, Columbia University Medical Center, New York, New York.
Philip S LiCenter for Male Reproductive Medicine and Microsurgery, Department of Urology, Weill Cornell Medicine of Cornell University, New York, New York.
James M HotalingDivision of Urology, Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah. Electronic address: jim.hotaling@hsc.utah.edu.
University of Utah · USCornell University · USColumbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many couples initially deferred attempts at pregnancy or delayed fertility care due to concerns about coronavirus disease 2019 (COVID-19). One significant fear during the COVID-19 pandemic was the possibility of sexual transmission. Many couples have since resumed fertility care while accepting the various uncertainties associated with severe acute respiratory syndrome coronavirus 2, including the evolving knowledge related to male reproductive health. Significant research has been conducted exploring viral shedding, tropism, sexual transmission, the impact of male reproductive hormones, and possible implications to semen quality. However, to date, limited definitive evidence exists regarding many of these aspects, creating a challenging landscape for both patients and physicians to obtain and provide the best clinical care. This review provides a comprehensive assessment of the evolving literature concerning COVID-19 and male sexual and reproductive health, and guidance for patient counseling.

Indexed as

COVID-19Genitalia, MaleHumansInfertility, MaleMaleMen's HealthReproductionReproductive HealthSARS-CoV-2angiotensin-converting enzyme 2coronavirusCOVID-19infertilitymalesemen

Identifiers

PMID33509629
PMCPMC7775791
OpenAlexW3116311437

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.