Evidence map›Paper›PMID 33509436›Full record

ArticleSpatial and spatio-temporal epidemiology2021

A Bayesian approach to improving spatial estimates of prevalence of COVID-19 after accounting for misclassification bias in surveillance data in Philadelphia, PA.

Neal D Goldstein, David C Wheeler, Paul Gustafson, Igor Burstyn

Abstract read
In one paragraph

Article in Spatial and spatio-temporal epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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  8. Antibody Responses in COVID-19: A Review.Frontiers in immunology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Neal D GoldsteinDepartment of Epidemiology & Biostatistics, Drexel University Dornsife School of Public Health, 3215 Market St., Philadelphia, PA 19104, USA. Electronic address: ng338@drexel.edu.
David C WheelerDepartment of Biostatistics, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.
Paul GustafsonDepartment of Statistics, University of British Columbia, Vancouver, BC, Canada.
Igor BurstynDepartment of Epidemiology & Biostatistics, Drexel University Dornsife School of Public Health, 3215 Market St., Philadelphia, PA 19104, USA; Department of Environmental and Occupational Health, Drexel University Dornsife School of Public Health, Philadelphia, PA, USA.

Funding

Towards prevention of HIV among vulnerable and stigmatized populations using geospatial dataK01AI143356 · NIAID · DREXEL UNIVERSITY · PI GOLDSTEIN, NEAL D · 2019 to 2023
$607k
NIAID NIH HHS K01 AI143356
6 · The paper itself

Abstract

Surveillance data obtained by public health agencies for COVID-19 are likely inaccurate due to undercounting and misdiagnosing. Using a Bayesian approach, we sought to reduce bias in the estimates of prevalence of COVID-19 in Philadelphia, PA at the ZIP code level. After evaluating various modeling approaches in a simulation study, we estimated true prevalence by ZIP code with and without conditioning on an area deprivation index (ADI). As of June 10, 2020, in Philadelphia, the observed citywide period prevalence was 1.5%. After accounting for bias in the surveillance data, the median posterior citywide true prevalence was 2.3% when accounting for ADI and 2.1% when not. Overall the median posterior surveillance sensitivity and specificity from the models were similar, about 60% and more than 99%, respectively. Surveillance of COVID-19 in Philadelphia tends to understate discrepancies in burden for the more affected areas, potentially misinforming mitigation priorities.

Indexed as

Bayes TheoremPopulation SurveillanceSpatial AnalysisBiasCOVID-19HumansPhiladelphiaPrevalenceSARS-CoV-2Sensitivity and SpecificityBayesian analysisCOVID-19MisclassificationSARS-CoV-2Surveillance

Identifiers

PMID33509436
PMCPMC7833121

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.