Evidence map›Paper›PMID 33509428›Full record

ArticleSpatial and spatio-temporal epidemiology2021

Modelling airport catchment areas to anticipate the spread of infectious diseases across land and air travel.

Carmen Huber, Alexander Watts, Ardath Grills, Jean Hai Ein Yong, Stephanie Morrison, Sarah Bowden, Ashleigh Tuite, Bradley Nelson, Martin Cetron, Kamran Khan

Abstract readCase Reports
In one paragraph

Article in Spatial and spatio-temporal epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carmen HuberBlueDot, 207 Queens Quay West #801b, Toronto, Ontario, Canada. Electronic address: carmen@bluedot.global.
Alexander WattsBlueDot, 207 Queens Quay West #801b, Toronto, Ontario, Canada.
Ardath GrillsDivision of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases, 1600 Clifton Road, Atlanta, GA, United States of America (USA).
Jean Hai Ein YongBlueDot, 207 Queens Quay West #801b, Toronto, Ontario, Canada.
Stephanie MorrisonDivision of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases, 1600 Clifton Road, Atlanta, GA, United States of America (USA); Eagle Medical Services, LLC, 1826 Loop 1604 W, Suite 336-D, San Antonio, TX, United States of America (USA).
Sarah BowdenDivision of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases, 1600 Clifton Road, Atlanta, GA, United States of America (USA); Eagle Medical Services, LLC, 1826 Loop 1604 W, Suite 336-D, San Antonio, TX, United States of America (USA).
Ashleigh TuiteBlueDot, 207 Queens Quay West #801b, Toronto, Ontario, Canada.
Bradley NelsonDivision of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases, 1600 Clifton Road, Atlanta, GA, United States of America (USA).
Martin CetronDivision of Global Migration and Quarantine, National Center for Emerging and Zoonotic Infectious Diseases, 1600 Clifton Road, Atlanta, GA, United States of America (USA).
Kamran KhanBlueDot, 207 Queens Quay West #801b, Toronto, Ontario, Canada; Department of Medicine, Division of Infectious Diseases, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute, St. Michael's Hospital, 38 Shuter St, Toronto, Ontario, Canada.

Funding

Intramural CDC HHS CC999999NCEZID CDC HHS U2G CK000433
6 · The paper itself

Abstract

Air travel is an increasingly important conduit for the worldwide spread of infectious diseases. However, methods to identify which airports an individual may use to initiate travel, or where an individual may travel to upon arrival at an airport is not well studied. This knowledge gap can be addressed by estimating airport catchment areas: the geographic extent from which the airport derives most of its patronage. While airport catchment areas can provide a simple decision-support tool to help delineate the spatial extent of infectious disease spread at a local scale, observed data for airport catchment areas are rarely made publicly available. Therefore, we evaluated a probabilistic choice behavior model, the Huff model, as a potential methodology to estimate airport catchment areas in the United States in data-limited scenarios. We explored the impact of varying input parameters to the Huff model on estimated airport catchment areas: distance decay exponent, distance cut-off, and measures of airport attractiveness. We compared Huff model catchment area patterns for Miami International Airport (MIA) and Harrisburg International Airport (MDT). We specifically compared our model output to observed data sampled for MDT to align model parameters with an established, observed catchment area. Airport catchment areas derived using the Huff model were highly sensitive to changes in model parameters. We observed that a distance decay exponent of 2 and a distance cut-off of 500 km represented the most realistic spatial extent and heterogeneity of the MIA catchment area. When these parameters were applied to MDT, the Huff model produced similar spatial patterns to the observed MDT catchment area. Finally, our evaluation of airport attractiveness showed that travel volume to the specific international destinations of interest for infectious disease importation risks (i.e., Brazil) had little impact on the predicted choice of airport when compared to all international travel. Our work is a proof of concept for use of the Huff model to estimate airport catchment areas as a generalizable decision-support tool in data-limited scenarios. While our work represents an initial examination of the Huff model as a method to approximate airport catchment areas, an essential next step is to conduct a quantitative calibration and validation of the model based on multiple airports, possibly leveraging local human mobility data such as call detail records or online social network data collected from mobile devices. Ultimately, we demonstrate how the Huff model could be potentially helpful to improve the precision of early warning systems that anticipate infectious disease spread, or to incorporate when local public health decision makers need to identify where to mobilize screening infrastructure or containment strategies at a local level.

Indexed as

Air TravelCommunicable DiseasesAirportsHumansModels, StatisticalPublic HealthAirport catchment areaHuff modelInfectious disease spreadPublic health

Identifiers

PMID33509428
PMCPMC10413988

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.