Evidence map›Paper›PMID 33509351›Full record

ArticleKidney international2021

"To take or not to take an aspirin?" The age-old question of cardiovascular disease primary prevention for people with chronic kidney disease.

Rupert W Major, James O Burton

Abstract readComment
PubMed Publisher
In one paragraph

Article in Kidney international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Rupert W MajorJohn Walls Renal Unit, University Hospitals of Leicester, Leicester General Hospital, Leicester, UK; Department of Health Sciences, University of Leicester, Leicester, UK. Electronic address: rwlm2@le.ac.uk.
James O BurtonJohn Walls Renal Unit, University Hospitals of Leicester, Leicester General Hospital, Leicester, UK; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Leicester General Hospital · GBUniversity of Leicester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the higher risk of cardiovascular events in patients with chronic kidney disease, the role of aspirin for primary prevention is unclear. In the current issue, Wolfe et al. present a subgroup analysis of the ASPirin in Reducing Events in the Elderly (ASPREE) trial that suggests there was no reduction in cardiovascular events but bleeding events were doubled. Aspirin cannot be recommended for primary prevention in chronic kidney disease, but the continuation of ongoing research, such as the Aspirin To Target Arterial Events in Chronic Kidney Disease (ATTACK trial), is warranted.

Indexed as

Cardiovascular DiseasesRenal Insufficiency, ChronicAgedAspirinHemorrhageHumansPrimary PreventionAspirin

Identifiers

PMID33509351
OpenAlexW3125866273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.