Evidence map›Paper›PMID 33509312›Full record

ArticleJournal of the International Neuropsychological Society : JINS2021

Personality Characteristics and Acute Symptom Response Predict Chronic Symptoms After Mild Traumatic Brain Injury.

Hillary A Parker, Jana Ranson, Michael A McCrea, James Hoelzle, Terri deRoon-Cassini, Lindsay D Nelson

Open access · greenAbstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Hillary A ParkerDepartment of Neurology, Mount Carmel Health System, Columbus, OH, USA.ORCID 0000-0002-8610-5975
Jana RansonDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0003-0967-192X
Michael A McCreaClement J. Zablocki VA Medical Center, Milwaukee, WI, USA.
James HoelzleDepartment of Psychology, Marquette University, Milwaukee, WI, USA.
Terri deRoon-CassiniDepartment of Surgery, Division of Trauma and Acute Care Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Lindsay D NelsonDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0001-5258-953X
Medical College of Wisconsin · USMarquette University · USMount Carmel Health · US

Funding

Clincal and Translational Science AwardUL1TR000055 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2012 to 2015
$11.3M
Improving Patient Classification and Outcome Measurement in Traumatic Brain Injury (TBI)R01NS110856 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI NELSON, LINDSAY · 2019 to 2023
$3.0M
NCATS NIH HHS UL1 TR000055NINDS NIH HHS R01 NS110856
6 · The paper itself

Abstract

objectiveDespite consensus that personality influences mild traumatic brain injury (mTBI) recovery, it has been underexamined. We evaluated the extent to which diverse personality and psychiatric symptom dimensions predict mTBI recovery.

methodsThis prospective cohort study involved psychological assessments of hospital patients with mTBI (n = 75; median = 2 days post-injury, range = 0-12 days) and orthopedic trauma controls (OTC; n = 79) who were used for comparison in mediation modeling. Chronic symptoms were evaluated at 3 months after mTBI (n = 50) using the Sport Concussion Assessment Tool (SCAT) symptom checklist. Linear regression analyses were used to identify the predominant predictors of chronic symptoms in mTBI. Modern mediation analyses tested the hypothesis that personality traits predict chronic symptoms through acute psychological response to injury.

resultsIn mTBI, trait psychoticism directly predicted chronic mTBI symptoms and was the strongest personality predictor overall. Furthermore, an internalizing personality dimension emphasizing negative affect/emotionality and detachment predicted chronic mTBI symptoms indirectly through enhancement of acute somatic complaints. In OTC, internalizing personality acted through the same mediator as in mTBI, whereas the effect of psychoticism was also mediated through acute somatic complaints. There was varying support for a moderated direct effect of personality traits at low levels of positive emotionality across models.

conclusionThese causal models provide novel insights about the role of personality in mTBI symptom recovery, highlighting the complexity of how psychological processes may interact to affect recovery and revealing that some of these processes may be non-specific to brain injury.

Indexed as

Brain ConcussionBrain InjuriesMental DisordersPost-Concussion SyndromeHumansPersonalityProspective StudiesAffectBrain concussionHuman characteristicsPost-concussion syndromePsychologyRecovery of function

Identifiers

PMID33509312
PMCPMC8319217
OpenAlexW3123827939

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.