Evidence map›Paper›PMID 33509307›Full record

ReviewThe British journal of nutrition2021

Diets, nutrients, genes and the microbiome: recent advances in personalised nutrition.

Nathan V Matusheski, Aoife Caffrey, Lars Christensen, Simon Mezgec, Shelini Surendran, Mads F Hjorth, Helene McNulty, Kristina Pentieva, Henrik M Roager, Barbara Koroušić Seljak and 3 more

Open access · hybridAbstract readReview
In one paragraph

Review in The British journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Review
  8. Correlation Between Dysbiosis and Atrial Fibrillation: What's New?International journal of molecular sciences · 2025
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Neonatal Microbiome: Is it Still Beneficial?Endocrine, metabolic & immune disorders drug targets · 2024
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Nathan V MatusheskiNutrition Science and Advocacy, DSM Nutritional Products LLC, Parsippany, NJ, USA.ORCID 0000-0002-0746-5228
Aoife CaffreyNutrition Innovation Centre for Food and Health (NICHE), School of Biomedical Sciences, Ulster University, ColeraineBT52 1SA, Northern Republic of Ireland.ORCID 0000-0002-7991-7262
Lars ChristensenDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Rolighedsvej 26, 1958 Frederiksberg, Frederiksberg, Denmark.
Simon MezgecJožef Stefan International Postgraduate School, Jamova cesta 39, 1000Ljubljana, Slovenia.ORCID 0000-0003-1663-3286
Shelini SurendranHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Whiteknights, ReadingRG6 6DZ, UK.
Mads F HjorthDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Rolighedsvej 26, 1958 Frederiksberg, Frederiksberg, Denmark.ORCID 0000-0001-9440-2737
Helene McNultyNutrition Innovation Centre for Food and Health (NICHE), School of Biomedical Sciences, Ulster University, ColeraineBT52 1SA, Northern Republic of Ireland.
Kristina PentievaNutrition Innovation Centre for Food and Health (NICHE), School of Biomedical Sciences, Ulster University, ColeraineBT52 1SA, Northern Republic of Ireland.ORCID 0000-0003-2059-534X
Henrik M RoagerDepartment of Nutrition, Exercise and Sports, Faculty of Science, University of Copenhagen, Rolighedsvej 26, 1958 Frederiksberg, Frederiksberg, Denmark.ORCID 0000-0002-2504-8313
Barbara Koroušić SeljakComputer Systems Department, Jožef Stefan Institute, Jamova cesta 39, 1000 Ljubljana, Ljubljana, Slovenia.ORCID 0000-0001-7597-2590
Karani Santhanakrishnan VimaleswaranHugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences, University of Reading, Whiteknights, ReadingRG6 6DZ, UK.ORCID 0000-0002-8485-8930
Marcus RemmersKoninklijke DSM N.V., Geleen, The Netherlands.
Szabolcs PéterNutrition Innovation Center, DSM Nutritional Products Ltd, Kaiseraugst, Switzerland.ORCID 0000-0002-6427-1606
University of Copenhagen · DKUniversity of Ulster · GBUniversity of Reading · GBDSM (Netherlands) · NLJožef Stefan Institute · SIJožef Stefan International Postgraduate School · SI

Funding

Biotechnology and Biological Sciences Research Council BB/S020330/1Medical Research Council MR/S024778/1
6 · The paper itself

Abstract

As individuals seek increasingly individualised nutrition and lifestyle guidance, numerous apps and nutrition programmes have emerged. However, complex individual variations in dietary behaviours, genotypes, gene expression and composition of the microbiome are increasingly recognised. Advances in digital tools and artificial intelligence can help individuals more easily track nutrient intakes and identify nutritional gaps. However, the influence of these nutrients on health outcomes can vary widely among individuals depending upon life stage, genetics and microbial composition. For example, folate may elicit favourable epigenetic effects on brain development during a critical developmental time window of pregnancy. Genes affecting vitamin B12 metabolism may lead to cardiometabolic traits that play an essential role in the context of obesity. Finally, an individual's gut microbial composition can determine their response to dietary fibre interventions during weight loss. These recent advances in understanding can lead to a more complete and integrated approach to promoting optimal health through personalised nutrition, in clinical practice settings and for individuals in their daily lives. The purpose of this review is to summarise presentations made during the DSM Science and Technology Award Symposium at the 13th European Nutrition Conference, which focused on personalised nutrition and novel technologies for health in the modern world.

Indexed as

DietGastrointestinal MicrobiomeNutrigenomicsDietary FiberHumansNutrientsPrecision MedicineDietary FiberNutrientsDeep learningEpigeneticsFolateMicrobiomeObesityPersonalised nutritionVitamin B12

Identifiers

PMID33509307
PMCPMC8524424
OpenAlexW3124966662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.