Evidence map›Paper›PMID 33509286›Full record

ArticleVeterinary research2021

Efficacy of a multivalent vaccine against Fasciola hepatica infection in sheep.

Rafael Zafra, Leandro Buffoni, Raúl Pérez-Caballero, Verónica Molina-Hernández, María T Ruiz-Campillo, José Pérez, Álvaro Martínez-Moreno, Francisco J Martínez Moreno

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Evaluation ofVaccines · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Harnessing mRNA technology againstFrontiers in immunology · 2025
    Article
  7. Advancement in Diagnosis, Treatment, and Vaccines againstPathogens (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Liver Histopathological and Immunohistochemical Evaluation fromAnimals : an open access journal from MDPI · 2024
    Article
  10. Article
  11. Article
  12. An Update on the Pathogenesis of Fascioliasis: What Do We Know?Research and reports in tropical medicine · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Fasciolosis-An Increasing Challenge in the Sheep Industry.Animals : an open access journal from MDPI · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rafael ZafraAnimal Health Department (Parasitology and Parasitic Diseases), Faculty of Veterinary Medicine, University of Córdoba, Sanidad Animal Building, Rabanales Campus, Córdoba, Spain.
Leandro BuffoniAnimal Health Department (Parasitology and Parasitic Diseases), Faculty of Veterinary Medicine, University of Córdoba, Sanidad Animal Building, Rabanales Campus, Córdoba, Spain. h12bupel@uco.es.ORCID http://orcid.org/0000-0003-2983-7288
Raúl Pérez-CaballeroAnimal Health Department (Parasitology and Parasitic Diseases), Faculty of Veterinary Medicine, University of Córdoba, Sanidad Animal Building, Rabanales Campus, Córdoba, Spain.
Verónica Molina-HernándezDepartment of Anatomy, Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Sanidad Animal Building, Rabanales Campus, Córdoba, Spain.
María T Ruiz-CampilloDepartment of Anatomy, Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Sanidad Animal Building, Rabanales Campus, Córdoba, Spain.
José PérezDepartment of Anatomy, Comparative Pathology and Toxicology, Faculty of Veterinary Medicine, University of Córdoba, Sanidad Animal Building, Rabanales Campus, Córdoba, Spain.
Álvaro Martínez-MorenoAnimal Health Department (Parasitology and Parasitic Diseases), Faculty of Veterinary Medicine, University of Córdoba, Sanidad Animal Building, Rabanales Campus, Córdoba, Spain.
Francisco J Martínez MorenoAnimal Health Department (Parasitology and Parasitic Diseases), Faculty of Veterinary Medicine, University of Córdoba, Sanidad Animal Building, Rabanales Campus, Córdoba, Spain.
University of Córdoba · ES

Funding

Horizon 2020 Framework Programme 635408-PARAGONE
6 · The paper itself

Abstract

In this work we report the protection found in a vaccination trial performed in sheep with two different vaccines composed each one by a cocktail of antigens (rCL1, rPrx, rHDM and rLAP) formulated in two different adjuvants (Montanide ISA 61 VG (G1) and Alhydrogel

Indexed as

Adjuvants, ImmunologicAnimalsFasciola hepaticaFascioliasisSheepSheep DiseasesSheep, DomesticVaccinationVaccines, CombinedAdjuvants, ImmunologicVaccines, CombinedFasciola hepaticaProtectionSheepVaccine

Identifiers

PMID33509286
PMCPMC7841919
OpenAlexW3122413231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.