Evidence map›Paper›PMID 33509192›Full record

Trial reportJournal of neuroengineering and rehabilitation2021

Investigating the feasibility of cerebellar transcranial direct current stimulation to facilitate post-stroke overground gait performance in chronic stroke: a partial least-squares regression approach.

Dhaval Solanki, Zeynab Rezaee, Anirban Dutta, Uttama Lahiri

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 5 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  6. Trial
  7. Review
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  9. Article
  10. Review
  11. A Brief History of Cerebellar Neurostimulation.Cerebellum (London, England) · 2022
    Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Dhaval Solanki *Electrical Engineering, Indian Institute of Technology Gandhinagar, Gujarat, India. dhaval.solanki@iitgn.ac.in.
Zeynab Rezaee *Biomedical Engineering, University at Buffalo SUNY, New York, USA.
Anirban Dutta *Biomedical Engineering, University at Buffalo SUNY, New York, USA. anirband@buffalo.edu.ORCID 0000-0002-7298-9773
Uttama Lahiri *Electrical Engineering, Indian Institute of Technology Gandhinagar, Gujarat, India.
Indian Institute of Technology Gandhinagar · INUniversity at Buffalo, State University of New York · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInvestigation of lobule-specific electric field effects of cerebellar transcranial direct current stimulation (ctDCS) on overground gait performance has not been performed, so this study aimed to investigate the feasibility of two lobule-specific bilateral ctDCS montages to facilitate overground walking in chronic stroke.

methodsTen chronic post-stroke male subjects participated in this repeated-measure single-blind crossover study, where we evaluated the single-session effects of two bilateral ctDCS montages that applied 2 mA via 3.14 cm

resultsThe ctDCS montage specific effect was found significant using a two-sided Wilcoxon rank-sum test at a 5% significance level for 'Step Time Affected Leg' (p = 0.0257) and '%Stance Time Unaffected Leg' (p = 0.0376). The changes in the quantitative gait parameters were found to be correlated to the mean electric field strength in the lobules based on PLSR analysis (R

conclusionOur feasibility study found an association between the lobular mean electric field strength and the changes in the quantitative gait parameters following a single ctDCS session in chronic stroke. Both the ctDCS montages improved the clinical outcome measures that should be investigated with a larger sample size for clinical validation.

trial registrationBeing retrospectively registered.

Indexed as

CerebellumCross-Over StudiesFeasibility StudiesGait Disorders, NeurologicHumansLeast-Squares AnalysisMaleMiddle AgedSingle-Blind MethodStrokeStroke RehabilitationTranscranial Direct Current StimulationCerebellumGaitStrokeTranscranial direct current stimulation

Identifiers

PMID33509192
PMCPMC7842063
OpenAlexW3110272231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.