ArticleBMC endocrine disorders2021
The association between diabetes and thyroid cancer risk: a hospital-based case-control study in China.
Article in BMC endocrine disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 14 citations in OpenAlex.
- Analysis of the association between water iodine concentration and TyG-BMI index with thyroid diseases: a cross-sectional study in Shandong province, China.Frontiers in nutrition · 2026Article
- Mechanistic study of quercetin in the treatment of thyroid cancer with diabetes based on network pharmacology andFrontiers in endocrinology · 2025Article
- Glucagon-like peptide 1 receptor agonist use and risk of thyroid cancer: Scandinavian cohort study.BMJ (Clinical research ed.) · 2024Article
- Thyroid cancer and insulin resistance.Reviews in endocrine & metabolic disorders · 2024Review
- Relationship between METS-IR and thyroid cancer incidence in Korea: a nationwide population-based study.Frontiers in oncology · 2024Article
- Metabolic syndrome and thyroid Cancer: risk, prognosis, and mechanism.Discover oncology · 2023Review
- Thyroid nodule malignancy is associated with increased non-invasive hepatic fibrosis scores in metabolic subjects.Frontiers in oncology · 2023Article
- Review
- Thyroid Cancer Burden in China: 1990 to 2021 Trends and 15-Year Projections Against Global Trends.OTO openArticle
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Authors and funding
6 authors at 1 institution in 1 country.
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Abstract
backgroundPrevious studies have indicated inconsistent relationships of diabetes with thyroid cancer risk, yet little is known in China. In this study, we aimed to investigate the associations between diabetes, diabetes duration and the risk of thyroid cancer in Chinese population.
methodsA 1:1 matched case-control study was performed between 2015 and 2017 in Zhejiang Province including 2,937 thyroid cancer cases and 2,937 healthy controls. Odds ratios (ORs) with 95 % confidence intervals (CIs) for thyroid cancer were estimated in logistic regression models. Specific effects stratified by age, as well as sex, body mass index (BMI) and family history of diabetes were also examined.
resultsOverall, neither diabetes (OR = 0.75, 95 % CI: 0.21-2.73) nor diabetes duration (OR = 0.14, 95 % CI: 0.02-1.22 for diabetes duration ≦ 5 years; OR = 2.10, 95 % CI: 0.32-13.94 for diabetes duration > 5 years) was significantly associated with thyroid cancer. In stratified analyses, significant lower risk of thyroid cancer was observed among subjects with diabetes and shorter diabetes duration ( ≦ 5 years), but limited to those who were aged more than 40 years, female, overweight/obese and had positive family history of diabetes.
conclusionsDiabetes and shorter diabetes duration were significantly associated with decreased risk of thyroid cancer in individuals characterized by older age, female sex, higher BMI and positive family history of diabetes.
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