Evidence map›Paper›PMID 33509081›Full record

ArticleBMC immunology2021

Clinical observations of bone marrow transfusion for promoting bone marrow reconstruction after chemotherapy for AIDS-related lymphoma.

Yixuan Liu, Suhong Xie, Lei Li, Yanhui Si, Weiwei Zhang, Xin Liu, Lin Guo, Baochi Liu, Renquan Lu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yixuan Liu *Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, No.270, Dong'An Road, Xuhui District, Shanghai, 200032, China.
Suhong Xie *Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, No.270, Dong'An Road, Xuhui District, Shanghai, 200032, China.
Lei LiDepartment of surgery, Shanghai Public Health Clinical Center, Affiliated to Fudan University, Shanghai, China.
Yanhui SiDepartment of surgery, Shanghai Public Health Clinical Center, Affiliated to Fudan University, Shanghai, China.
Weiwei ZhangDepartment of surgery, Shanghai Public Health Clinical Center, Affiliated to Fudan University, Shanghai, China.
Xin LiuDepartment of surgery, Shanghai Public Health Clinical Center, Affiliated to Fudan University, Shanghai, China.
Lin GuoDepartment of Clinical Laboratory, Fudan University Shanghai Cancer Center, No.270, Dong'An Road, Xuhui District, Shanghai, 200032, China.
Baochi LiuDepartment of surgery, Shanghai Public Health Clinical Center, Affiliated to Fudan University, Shanghai, China.
Renquan LuDepartment of Clinical Laboratory, Fudan University Shanghai Cancer Center, No.270, Dong'An Road, Xuhui District, Shanghai, 200032, China. lurenquan@126.com.
Shanghai Public Health Clinical Center · CNFudan University Shanghai Cancer Center · CNShanghai Medical College of Fudan University · CN

Funding

National Natural Science Foundation of China NSF-81772774National Natural Science Foundation of China NSF-81772808Science and Technology Commission of Shanghai Municipality 15411963100Science and Technology Commission of Shanghai Municipality (CN) 17411951000Science and Technology Commission of Shanghai Municipality (CN) 17411963500
6 · The paper itself

Abstract

backgroundThis study investigates the effect of autologous bone marrow transfusion (BMT) on the reconstruction of both bone marrow and the immune system in patients with AIDS-related lymphoma (ARL).

methodsA total of 32 patients with ARL participated in this study. Among them, 16 participants were treated with conventional surgery and chemotherapy (control group) and the remaining 16 patients were treated with chemotherapy followed by autologous bone marrow transfusion via a mesenteric vein (8 patients, ABM-MVI group) or a peripheral vein (8 patients, ABM-PI group). Subsequently, peripheral blood and lymphocyte data subsets were detected and documented in all patients.

resultsBefore chemotherapy, no significant difference in indicators was observed between three groups of ARL patients. Unexpectedly, 2 weeks after the end of 6 courses of chemotherapy, the ABM-MVI group, and the ABM-PI group yielded an increased level of CD8

conclusionsAutologous bone marrow transfusion after chemotherapy can promote the reconstruction of both bone marrow and the immune system. There was no significant difference in bone marrow recovery and reconstruction between the mesenteric vein transfusion group and the peripheral vein transfusion group.

Indexed as

AdultAgedAnti-Retroviral AgentsBlood Cell CountBlood PlateletsBone MarrowCombined Modality TherapyFemaleHematopoietic Stem Cell TransplantationHemoglobinsHumansLeukocytesLymphoma, AIDS-RelatedMaleMiddle AgedSurvival RateAnti-Retroviral AgentsHemoglobinsAIDS-related lymphomaAutologous bone marrow transfusionBone marrow reconstructionChemotherapy

Identifiers

PMID33509081
PMCPMC7845098
OpenAlexW3124235096

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.