Evidence map›Paper›PMID 33509059›Full record

ReviewThe veterinary quarterly2021

Advances in therapeutic and managemental approaches of bovine mastitis: a comprehensive review.

Khan Sharun, Kuldeep Dhama, Ruchi Tiwari, Mudasir Bashir Gugjoo, Mohd Iqbal Yatoo, Shailesh Kumar Patel, Mamta Pathak, Kumaragurubaran Karthik, Sandip Kumar Khurana, Rahul Singh and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in The veterinary quarterly, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 159 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
159citing papers in PubMed, 2 pooled it
55.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

159 citing papers in PubMed, 2 syntheses or guidelines pooled it, 324 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  17. Microorganisms · 2026
    Review
  18. Article
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99 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Khan SharunDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.ORCID https://orcid.org/0000-0003-1040-3746
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.ORCID https://orcid.org/0000-0001-7469-4752
Ruchi TiwariDepartment of Veterinary Microbiology and Immunology, College of Veterinary Sciences, Deen Dayal Upadhayay Pashu Chikitsa Vigyan Vishwavidyalay Evum Go-Anusandhan Sansthan (DUVASU), Mathura, India.ORCID https://orcid.org/0000-0001-6897-3472
Mudasir Bashir GugjooDivision of Veterinary Clinical Complex, Faculty of Veterinary Sciences & Animal Husbandry, Sher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shalimar, Srinagar, Jammu and Kashmir, India.ORCID https://orcid.org/0000-0003-1237-4184
Mohd Iqbal YatooSher-E-Kashmir University of Agricultural Sciences and Technology of Kashmir, Shalimar, Srinagar, Jammu and Kashmir, India.ORCID https://orcid.org/0000-0002-4501-7354
Shailesh Kumar PatelDivision of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Mamta PathakDivision of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Kumaragurubaran KarthikCentral University Laboratory, Tamil Nadu Veterinary and Animal Sciences University, Chennai, Tamil Nadu, India.ORCID https://orcid.org/0000-0002-9215-6306
Sandip Kumar KhuranaICAR-Central Institute for Research on Buffaloes, Hisar, Haryana, India.
Rahul SinghDivision of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.ORCID https://orcid.org/0000-0001-5904-804X
Bhavani PuvvalaRajiv Gandhi Institute of Veterinary Education and Research, Kurumbapet, Puducherry, India.
AmarpalDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Rajendra SinghDivision of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.ORCID https://orcid.org/0000-0003-3127-3346
Karam Pal SinghDivision of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India.
Wanpen ChaicumpaCenter of Research Excellence on Therapeutic Proteins and Antibody Engineering, Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Indian Veterinary Research Institute · INSher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir · INCentral Institute for Research on Buffaloes · INMahatma Gandhi Medical College and Research Institute · INSiriraj Hospital · THTamil Nadu Veterinary and Animal Sciences University · INUttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mastitis (intramammary inflammation) caused by infectious pathogens is still considered a devastating condition of dairy animals affecting animal welfare as well as economically incurring huge losses to the dairy industry by means of decreased production performance and increased culling rates. Bovine mastitis is the inflammation of the mammary glands/udder of bovines, caused by bacterial pathogens, in most cases. Routine diagnosis is based on clinical and subclinical forms of the disease. This underlines the significance of early and rapid identification/detection of etiological agents at the farm level, for which several diagnostic techniques have been developed. Therapeutic regimens such as antibiotics, immunotherapy, bacteriocins, bacteriophages, antimicrobial peptides, probiotics, stem cell therapy, native secretory factors, nutritional, dry cow and lactation therapy, genetic selection, herbs, and nanoparticle technology-based therapy have been evaluated for their efficacy in the treatment of mastitis. Even though several strategies have been developed over the years for the purpose of managing both clinical and subclinical forms of mastitis, all of them lacked the efficacy to eliminate the associated etiological agent when used as a monotherapy. Further, research has to be directed towards the development of new therapeutic agents/techniques that can both replace conventional techniques and also solve the problem of emerging antibiotic resistance. The objective of the present review is to describe the etiological agents, pathogenesis, and diagnosis in brief along with an extensive discussion on the advances in the treatment and management of mastitis, which would help safeguard the health of dairy animals.

Indexed as

AnimalsAnti-Bacterial AgentsBacteriaCattleDairyingDrug Resistance, BacterialFemaleMastitis, BovineAnti-Bacterial Agentsbovinecowetiologymanagementmastitisreviewtherapeuticstreatmentwelfare

Identifiers

PMID33509059
PMCPMC7906113
OpenAlexW3123416597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.