Evidence map›Paper›PMID 33508881›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

Early liver transplantation after COVID-19 infection: The first report.

Anand V Kulkarni, Kumarswamy Parthasarathy, Pramod Kumar, Mithun Sharma, Raghuram Reddy, Krishna Chaitanya Akkaraju Venkata, Rajesh Gupta, Anand Gupta, Shakti Swaroop, Premkumar Giri Vishwanathan and 4 more

Open access · hybridAbstract readCase Reports
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Successful liver transplantation in patients with active SARS-CoV-2 infection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2022
    Article
  10. COVID-19 in donation and transplant.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Review
  11. Review
  12. An overview of COVID-19 in solid organ transplantation.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Coronavirus Disease 2019 and Liver Transplantation: Lessons from the First Year of the Pandemic.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Anand V KulkarniDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.ORCID 0000-0002-1240-1675
Kumarswamy ParthasarathyDepartment of Liver Transplantation and Hepatobiliary Surgery, Asian Institute of Gastroenterology, Hyderabad, India.
Pramod KumarDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Mithun SharmaDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Raghuram ReddyDepartment of Liver Transplantation and Hepatobiliary Surgery, Asian Institute of Gastroenterology, Hyderabad, India.
Krishna Chaitanya Akkaraju VenkataDepartment of Liver Transplantation and Hepatobiliary Surgery, Asian Institute of Gastroenterology, Hyderabad, India.
Rajesh GuptaDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Anand GuptaDepartment of Anaesthesia, Asian Institute of Gastroenterology, Hyderabad, India.
Shakti SwaroopDepartment of Anaesthesia, Asian Institute of Gastroenterology, Hyderabad, India.
Premkumar Giri VishwanathanDepartment of Anaesthesia, Asian Institute of Gastroenterology, Hyderabad, India.
Gayathri SenapathyDepartment of Radiology, Asian Institute of Gastroenterology, Hyderabad, India.
Palat B MenonDepartment of Liver Transplantation and Hepatobiliary Surgery, Asian Institute of Gastroenterology, Hyderabad, India.
Nageshwar D ReddyDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Nagaraja R PadakiDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Asian Institute of Gastroenterology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 (coronavirus disease 2019) has impacted solid organ transplantation (SOT) in many ways. Transplant centers have initiated SOT despite the COVID-19 pandemic. Although it is suggested to wait for 4 weeks after COVID-19 infection, there are no data to support or refute the timing of liver transplant after COVID-19 infection. Here we describe the course and outcomes of COVID-19-infected candidates and healthy living liver donors who underwent transplantation. A total of 38 candidates and 33 potential living donors were evaluated from May 20, 2020 until October 30, 2020. Ten candidates and five donors were reverse transcriptase-polymerase chain reaction (RT-PCR) positive for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pretransplant. Four candidates succumbed preoperatively. Given the worsening of liver disease, four candidates underwent liver transplant after 2 weeks due to the worsening of liver disease and the other two candidates after 4 weeks. Only one recipient died due to sepsis posttransplant. Three donors underwent successful liver donation surgery after 4 weeks of COVID-19 infection without any postoperative complications, and the other two were delisted (as the candidates expired). This report is the first to demonstrate the feasibility of elective liver transplant early after COVID-19 infection.

Indexed as

COVID-19Liver TransplantationOrgan TransplantationHumansPandemicsSARS-CoV-2Transplant Recipientsclinical research/practiceinfection and infectious agentsliver transplantation/hepatologyliver transplantation: living donor

Identifiers

PMID33508881
PMCPMC8013377
OpenAlexW3125816193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.