Evidence map›Paper›PMID 33508790›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2021

Rapid Symptom Improvement in Major Depressive Disorder Using Accelerated Repetitive Transcranial Magnetic Stimulation.

Soo-Jeong Kim, Sang Joon Son, Mi Jang, Byung-Hoon Kim, Seok Joo Hong, Lina Seo, Sun-Woo Choi, Jeong-Ho Seok, Jai Sung Noh

Abstract read
In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Non-inferiority of Accelerated vs. Repetitive Transcranial Magnetic Stimulation in Major Depressive Disorder: A Systematic Review.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Review
  3. Review
  4. Long-term Safety and Efficacy of Esketamine Nasal Spray Plus an Oral Antidepressant in Patients with Treatment-resistant Depression- an Asian Sub-group Analysis from the SUSTAIN-2 Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Soo-Jeong KimDepartment of Psychiatry, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9065-7492
Sang Joon SonDepartment of Psychiatry, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0001-7434-7996
Mi JangDepartment of Mental Health Services, National Center for Mental Health, Seoul, Korea.ORCID https://orcid.org/0000-0003-4558-1171
Byung-Hoon KimDepartment of Psychiatry, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2501-038X
Seok Joo HongDepartment of Psychiatry, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0003-3191-7287
Lina SeoDepartment of Psychiatry, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-2681-4518
Sun-Woo ChoiInstitute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0755-9387
Jeong-Ho SeokDepartment of Psychiatry, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9402-7591
Jai Sung NohDepartment of Psychiatry, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-9610-0756

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRepetitive transcranial magnetic stimulation (rTMS) has contributed to increase in the remission rate for patients with major depressive disorder (MDD). However, current rTMS treatment is practically inconvenient because it requires daily treatment sessions for several weeks. Accelerated rTMS treatment is as efficient and safe for MDD patients as conventional rTMS.

methodsFifty-one patients with MDD participated in this study; they were randomized into accelerated rTMS (n = 21), conventional rTMS (n = 22), and sham-treatment (n = 8) groups. The accelerated and conventional rTMS groups received 15 sessions for 3 days and 3 weeks, respectively. The sham-treatment group received 15 sham rTMS sessions for 3 days. Primary outcome was assessed using self-report and clinician-rated Korean Quick Inventory of Depressive Symptomatology (KQIDS-SR and KQIDS-C, respectively). Adverse effects were monitored using the Frequency, Intensity, and Burden of Side Effects Rating scale. Changes in depressive symptoms were compared among the three groups using mixed model analyses.

resultsFor the KQIDS-SR score, there was a significant main effect of "time" (F

conclusionThe accelerated rTMS treatment group showed rapid improvement of depressive symptoms compared with the sham-treatment and conventional rTMS treatment groups. Therefore, accelerated rTMS treatment could be a viable option for MDD, with improved accessibility.

Indexed as

AccessibilityEffectivenesshealth servicesMajor depressive disorderrepetitiveSafetyTranscranial magnetic stimulationtreatment

Identifiers

PMID33508790
PMCPMC7851468

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.